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Condensed Consolidated Statements of Operations (USD $)
In Thousands, except Per Share data, unless otherwise specified
 3 Months Ended
Mar. 31, 2012
Mar. 31, 2011
Revenues:    
Collaboration revenue $ 929 $ 366
Grant revenue 1,087 889
Service and license revenue 334 489
Total revenues 2,350 1,744
Operating expenses:    
Research and development 12,405 14,672
General and administrative 5,793 4,754
Amortization of intangible assets   245
Total operating expenses 18,198 19,671
Loss from operations (15,848) (17,927)
Interest income 52 33
Interest expense (587) (490)
Other expense (122) (82)
Net loss $ (16,505) $ (18,466)
Basic and diluted net loss per share $ (0.11) $ (0.16)
Shares used to compute basic and diluted net loss per share 155,431 115,726