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Condensed Consolidated Statements of Cash Flows (USD $)
In Thousands, unless otherwise specified
 3 Months Ended
Mar. 31, 2012
Mar. 31, 2011
Operating activities    
Net loss $ (16,505) $ (18,466)
Adjustments to reconcile net loss to net cash used in operating activities:    
Depreciation and amortization 292 360
Amortization of intangible assets   245
Non-cash interest associated with the note payable to Holdings 547 468
Fair value adjustment of the warrant and contingent liabilities to Holdings   (3)
Accretion of discounts and amortization of premiums of marketable securities 304 354
Stock-based compensation expense 2,322 1,480
Changes in operating assets and liabilities:    
Accounts receivable 8,152 (126)
Prepaid expenses and other current assets (738) (155)
Restricted cash and other assets (83) (61)
Accounts payable 318 (449)
Accrued liabilities and other long term liabilities (1,844) (2,785)
Deferred revenues (946) (357)
Net cash used in operating activities (8,181) (19,495)
Investing activities    
Purchases of marketable securities (32,836) (1,004)
Proceeds from maturities of marketable securities 27,425 18,145
Purchases of property and equipment, net (932) (141)
Net cash provided by (used in) investing activities (6,343) 17,000
Financing activities    
Proceeds from issuance of common stock, net of issuance costs   834
Proceeds from exercise of warrants 1,054  
Proceeds from employee stock purchase plan 128 40
Proceeds from exercise of stock options 1,071 65
Net cash provided by financing activities 2,253 939
Effect of exchange rate on cash and cash equivalents 83 74
Net decrease in cash and cash equivalents (12,188) (1,482)
Cash and cash equivalents at beginning of period 31,941 22,453
Cash and cash equivalents at end of period 19,753 20,971
Supplemental disclosure of cash flow information    
Disposal of fully depreciated property and equipment $ 5 $ 836