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Revenue Recognized (Detail) (USD $)
In Thousands, unless otherwise specified
3 Months Ended 9 Months Ended
Sep. 30, 2012
Sep. 30, 2011
Sep. 30, 2012
Sep. 30, 2011
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]        
Grant revenue $ 1,219 $ 658 $ 3,188 $ 2,437
National Institutes of Health
       
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]        
Grant revenue 1,219 658 3,188 2,437
National Institutes of Health | NIAID Contract
       
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]        
Grant revenue 1,100 534 2,840 1,650
National Institutes of Health | All Other
       
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]        
Grant revenue $ 119 $ 124 $ 348 $ 787