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Commitments and Contingencies - Additional Information (Detail)
 12 Months Ended 3 Months Ended 12 Months Ended 3 Months Ended 3 Months Ended 12 Months Ended
Dec. 31, 2012
USD ($)
Dec. 31, 2011
USD ($)
Dec. 31, 2010
USD ($)
Dec. 31, 2012
Deutsche Bank Securities
EUR (€)
Dec. 31, 2004
Berkeley, California (the "Berkeley Lease")
USD ($)
Dec. 31, 2012
Berkeley, California (the "Berkeley Lease")
Dec. 31, 2004
Berkeley, California (the "Berkeley Lease")
Contingency, A
USD ($)
Dec. 31, 2004
Berkeley, California (the "Berkeley Lease")
Contingency, A
Maximum
USD ($)
Dec. 31, 2004
Berkeley, California (the "Berkeley Lease")
Contingency, A
Minimum
Dec. 31, 2004
Berkeley, California (the "Berkeley Lease")
Contingency, B
Dec. 31, 2004
Berkeley, California (the "Berkeley Lease")
Contingency, B
Minimum
USD ($)
Dec. 31, 2012
Dusseldorf, Germany (the "Dusseldorf Lease")
Loss Contingencies [Line Items]                        
Operating leases expiration date           2018-06           2023-03
Rent expense, net $ 1,700,000 $ 1,700,000 $ 2,600,000                  
Deferred rent 600,000 600,000                    
Future minimum payment excluding sub lease agreement payment 41,000                      
Letter of credit pledged as security       200,000 400,000              
Terms of the lease         If the total amount of our cash, cash equivalents and marketable securities falls below $20 million for a period of more than 30 consecutive days during the lease term, the amount of the required security deposit will increase to $1.1 million, until such time as our projected cash and cash equivalents will exceed $20 million for the remainder of the lease term, or until our actual cash and cash equivalents remains above $20 million for a period of 12 consecutive months.              
Cash, cash equivalents and marketable securities 125,100,000             20,000,000     20,000,000  
Contingency period for cash, cash equivalents and marketable securities                 30 days 12 months    
Increase in amount of the security deposit             1,100,000          
Future payments obligation $ 9,900,000