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Selected Quarterly Financial Data (Detail) (USD $)
In Thousands, except Per Share data, unless otherwise specified
 3 Months Ended 12 Months Ended
Dec. 31, 2012
Sep. 30, 2012
Jun. 30, 2012
Mar. 31, 2012
Dec. 31, 2011
Sep. 30, 2011
Jun. 30, 2011
Mar. 31, 2011
Dec. 31, 2012
Dec. 31, 2011
Dec. 31, 2010
Selected Quarterly Financial Data [Line Items]                      
Revenues $ 1,806 $ 2,874 $ 2,684 $ 2,350 $ 11,427 $ 1,174 $ 7,269 $ 1,744 $ 9,714 $ 21,614 $ 23,950
Net loss $ (20,543) $ (17,791) $ (15,110) $ (16,505) $ (4,267) $ (15,229) $ (10,635) $ (18,466) $ (69,949) $ (48,597) $ (57,308)
Basic and diluted net loss per share $ (0.11) $ (0.10) $ (0.09) $ (0.11) $ (0.03) $ (0.12) $ (0.09) $ (0.16) $ (0.41) $ (0.39) $ (0.69)
Shares used to compute basic and diluted net loss per share 180,685 177,870 167,697 155,431 142,482 124,069 117,864 115,726 170,469 125,101 82,463