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Condensed Consolidated Statements of Operations (USD $)
In Thousands, except Per Share data, unless otherwise specified
 3 Months Ended
Mar. 31, 2013
Mar. 31, 2012
Revenues:    
Collaboration revenue $ 883 $ 929
Grant revenue 760 1,087
Service and license revenue 442 334
Total 2,085 2,350
Operating expenses:    
Research and development 14,164 12,405
General and administrative 8,800 5,793
Total operating expenses 22,964 18,198
Loss from operations (20,879) (15,848)
Interest income 72 52
Interest expense (32) (587)
Other income (expense) 14 (122)
Net loss $ (20,825) $ (16,505)
Basic and diluted net loss per share $ (0.11) $ (0.11)
Shares used to compute basic and diluted net loss per share 182,847 155,431