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Condensed Consolidated Statements of Operations (USD $)
In Thousands, except Per Share data, unless otherwise specified
 3 Months Ended 6 Months Ended
Jun. 30, 2013
Jun. 30, 2012
Jun. 30, 2013
Jun. 30, 2012
Revenues:        
Collaboration revenue $ 1,356 $ 1,623 $ 2,239 $ 2,552
Grant revenue 1,395 882 2,155 1,969
Service and license revenue 641 179 1,083 513
Total 3,392 2,684 5,477 5,034
Operating expenses:        
Research and development 12,805 11,376 26,969 23,781
General and administrative 7,636 5,957 16,436 11,750
Total operating expenses 20,441 17,333 43,405 35,531
Loss from operations (17,049) (14,649) (37,928) (30,497)
Interest income 54 65 126 117
Interest expense (27) (589) (59) (1,176)
Other income (expense) (142) 63 (128) (59)
Net loss $ (17,164) $ (15,110) $ (37,989) $ (31,615)
Basic and diluted net loss per share $ (0.09) $ (0.09) $ (0.21) $ (0.20)
Weighted-average shares used to compute basic and diluted net loss per share 182,913 167,697 182,934 161,564