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Condensed Consolidated Statements of Cash Flows (USD $)
In Thousands, unless otherwise specified
 6 Months Ended
Jun. 30, 2013
Jun. 30, 2012
Operating activities    
Net loss $ (37,989) $ (31,615)
Adjustments to reconcile net loss to net cash used in operating activities:    
Depreciation and amortization 646 592
Gain on disposal of property and equipment 4  
Accretion of discounts and amortization of premiums of marketable securities 530 638
Interest associated with long-term note payable to Holdings   1,095
Stock compensation expense 8,002 4,391
Changes in operating assets and liabilities:    
Accounts receivable (1,020) 8,243
Prepaid expenses and other current assets 811 (3,015)
Restricted cash and other assets 14 (69)
Accounts payable (913) (885)
Accrued liabilities and other long term liabilities (2,758) (820)
Deferred revenues (1,902) (2,425)
Net cash used in operating activities (34,575) (23,870)
Investing activities    
Purchases of marketable securities (29,527) (114,400)
Proceeds from maturities of marketable securities 74,911 70,085
Purchases of property and equipment, net (828) (1,403)
Net cash provided by (used in) investing activities 44,556 (45,718)
Financing activities    
Payments and proceeds from issuances of common stock and warrants, net of issuance costs (142) 70,819
Proceeds from exercise of stock options and restricted stock awards 30 1,343
Proceeds from employee stock purchase plan 147 128
Net cash provided by financing activities 35 72,290
Effect of exchange rate on cash and cash equivalents (30) (113)
Net increase in cash and cash equivalents 9,986 2,589
Cash and cash equivalents at beginning of year 7,599 31,941
Cash and cash equivalents at end of year 17,585 34,530
Non-cash investing and financing activities:    
Disposal of fully depreciated property and equipment 8 19
Net change in unrealized gain on marketable securities $ (41) $ (27)