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Subsequent Event - Additional Information (Detail) (USD $) In Thousands, unless otherwise specified | 12 Months Ended | 1 Months Ended
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Dec. 31, 2011 | Dec. 31, 2013 Astra Zeneca | Dec. 31, 2012 Astra Zeneca | Dec. 31, 2011 Astra Zeneca | Mar. 31, 2014 Astra Zeneca Subsequent Event
Subsequent Event [Line Items] |  |  |  |  |
Milestone revenue | $ 12,000 | $ 2,507 | $ 2,462 | $ 642 | $ 5,400

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- Definition The amount of consideration recognized during the period for the milestone or milestones. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 605 -SubTopic 28 -Section 50 -Paragraph 2 -Subparagraph (e) -URI http://asc.fasb.org/extlink&oid=19771982&loc=SL6892177-166501 + Details
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Period Type: | duration

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- Details
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