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Summary of Revenue Recognized under Various Agreements (Detail) (USD $) In Thousands, unless otherwise specified	3 Months Ended				9 Months Ended		12 Months Ended	1 Months Ended	3 Months Ended		9 Months Ended		3 Months Ended		9 Months Ended		3 Months Ended		9 Months Ended		3 Months Ended		9 Months Ended
	Sep. 30, 2014	Jun. 30, 2014	Sep. 30, 2013	Jun. 30, 2013	Sep. 30, 2014	Sep. 30, 2013	Dec. 31, 2011	Dec. 31, 2008 Glaxo, Smith, Kline	Sep. 30, 2014 Glaxo, Smith, Kline	Sep. 30, 2013 Glaxo, Smith, Kline	Sep. 30, 2014 Glaxo, Smith, Kline	Sep. 30, 2013 Glaxo, Smith, Kline	Sep. 30, 2014 Astra Zeneca	Sep. 30, 2013 Astra Zeneca	Sep. 30, 2014 Astra Zeneca	Sep. 30, 2013 Astra Zeneca	Jun. 30, 2014 National Institute Of Allergy And Infectious Diseases	Jun. 30, 2013 National Institute Of Allergy And Infectious Diseases	Sep. 30, 2014 National Institute Of Allergy And Infectious Diseases	Sep. 30, 2013 National Institute Of Allergy And Infectious Diseases	Jun. 30, 2014 National Institutes of Health	Jun. 30, 2013 National Institutes of Health	Sep. 30, 2014 National Institutes of Health	Sep. 30, 2013 National Institutes of Health
Product Information [Line Items]
Initial payment								$ 10,000	$ 631	$ 357	$ 1,893	$ 1,071	$ 180	$ 180	$ 540	$ 540
Subsequent payment													675		2,025
Milestone revenue							12,000						309	573	1,741	1,738
Total revenues	2,209		2,927		8,755	8,404			631	357	1,893	1,071	1,164	753	4,306	2,278
Grant revenue	$ 414	$ 414	$ 1,700	$ 1,700	$ 2,546	$ 3,855											$ 255	$ 1,465	$ 2,094	$ 3,125	$ 159	$ 235	$ 452	$ 730

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Subsequent payment.

+ References

No definition available.

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- Definition

Amount of deferred revenue recognized for transactions arising during the current reporting period. Deferred revenue is a liability as of the balance sheet date related to a revenue producing activity for which revenue has not yet been recognized. Generally, an Entity records deferred revenue when it receives consideration from a customer before achieving certain criteria that must be met for revenue to be recognized in conformity with GAAP.

+ References

Reference 1: http://www.xbrl.org/2003/role/presentationRef

-Publisher FASB

-Name Accounting Standards Codification

-Topic 605

-SubTopic 10

-Section S99

-Paragraph 1

-Subparagraph (SAB TOPIC 13.A.4(a).Q1)

-URI http://asc.fasb.org/extlink&oid=27012821&loc=d3e214044-122780



Reference 2: http://www.xbrl.org/2003/role/presentationRef

-Publisher SEC

-Name Staff Accounting Bulletin (SAB)

-Number Topic 13

-Section A

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Revenue earned during the period from non-repayable sum of money awarded to an entity to carry out a specific purpose as provided in grant agreements.

+ References

Reference 1: http://www.xbrl.org/2003/role/presentationRef

-Publisher FASB

-Name Accounting Standards Codification

-Topic 225

-SubTopic 10

-Section S99

-Paragraph 2

-Subparagraph (SX 210.5-03.1(e))

-URI http://asc.fasb.org/extlink&oid=26872669&loc=d3e20235-122688

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The amount of consideration recognized during the period for the milestone or milestones.

+ References

Reference 1: http://www.xbrl.org/2003/role/presentationRef

-Publisher FASB

-Name Accounting Standards Codification

-Topic 605

-SubTopic 28

-Section 50

-Paragraph 2

-Subparagraph (e)

-URI http://asc.fasb.org/extlink&oid=19771982&loc=SL6892177-166501

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Amount of revenue recognized from goods sold, services rendered, insurance premiums, or other activities that constitute an earning process. Includes, but is not limited to, investment and interest income before deduction of interest expense when recognized as a component of revenue, and sales and trading gain (loss).

+ References

Reference 1: http://www.xbrl.org/2003/role/presentationRef

-Publisher FASB

-Name Accounting Standards Codification

-Topic 225

-SubTopic 10

-Section S99

-Paragraph 2

-Subparagraph (SX 210.5-03.1)

-URI http://asc.fasb.org/extlink&oid=26872669&loc=d3e20235-122688



Reference 2: http://www.xbrl.org/2003/role/presentationRef

-Publisher SEC

-Name Regulation S-X (SX)

-Number 210

-Section 03

-Paragraph 1

-Article 5

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