Subsequent Events	6 Months Ended
Jun. 30, 2015
Subsequent Events [Abstract]
Subsequent Events	10. Subsequent Events In July 2015, we received additional cash of approximately $28.8 million resulting from sales of our common stock following the end of the quarter under our ATM Agreement. The ATM Agreement has concluded, as we have reached an aggregate of $50 million of gross proceeds from sales of our common stock as specified in the ATM Agreement. On July 9, 2015, we announced that the independent DSMB charged with periodically reviewing safety data from HBV-23, the ongoing Phase 3 clinical study of HEPLISAV-B, had completed its third prespecified review and recommended that the study continue unchanged, resulting in the achievement of Milestone A under the Loan Agreement with Hercules and providing us the option to draw down the $30.0 million second tranche at any time prior to September 30, 2015 pursuant to the agreement. No additional amount has been drawn down through the date of this quarterly report. Additionally, the loan amortization date is now August 1, 2016 and the Loan Maturity Date is now January 1, 2019. See Note 6 for terms disclosed under our Loan Agreement. On July 23, 2015, 17,430 shares of our Series B Convertible Preferred Stock were converted into 1,743,000 shares of common stock. As of July 23, 2015, no Series B Convertible Preferred Stock remained outstanding. On July 27, 2015, we completed an underwritten public offering of 5,227,273 shares of our common stock, including 681,818 shares sold pursuant to the full exercise of an overallotment option previously granted to the underwriters. All of the shares were offered at a price to the public of $27.50 per share. The net proceeds to us from this offering were approximately $134.8 million, after deducting the underwriting discount and other estimated offering expenses payable by us. Subsequent events noted have been evaluated through the date of this quarterly report on Form 10-Q.

10. Subsequent Events

In July 2015, we received additional cash of approximately $28.8 million resulting from sales of our common stock following the end of the quarter under our ATM Agreement. The ATM Agreement has concluded, as we have reached an aggregate of $50 million of gross proceeds from sales of our common stock as specified in the ATM Agreement.

On July 9, 2015, we announced that the independent DSMB charged with periodically reviewing safety data from HBV-23, the ongoing Phase 3 clinical study of HEPLISAV-B, had completed its third prespecified review and recommended that the study continue unchanged, resulting in the achievement of Milestone A under the Loan Agreement with Hercules and providing us the option to draw down the $30.0 million second tranche at any time prior to September 30, 2015 pursuant to the agreement. No additional amount has been drawn down through the date of this quarterly report. Additionally, the loan amortization date is now August 1, 2016 and the Loan Maturity Date is now January 1, 2019. See Note 6 for terms disclosed under our Loan Agreement.

On July 23, 2015, 17,430 shares of our Series B Convertible Preferred Stock were converted into 1,743,000 shares of common stock. As of July 23, 2015, no Series B Convertible Preferred Stock remained outstanding.

On July 27, 2015, we completed an underwritten public offering of 5,227,273 shares of our common stock, including 681,818 shares sold pursuant to the full exercise of an overallotment option previously granted to the underwriters. All of the shares were offered at a price to the public of $27.50 per share. The net proceeds to us from this offering were approximately $134.8 million, after deducting the underwriting discount and other estimated offering expenses payable by us.

Subsequent events noted have been evaluated through the date of this quarterly report on Form 10-Q.