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Amount of deferred revenue recognized for transactions arising during the current reporting period. Deferred revenue is a liability as of the balance sheet date related to a revenue producing activity for which revenue has not yet been recognized. Generally, an Entity records deferred revenue when it receives consideration from a customer before achieving certain criteria that must be met for revenue to be recognized in conformity with GAAP.

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Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table.

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Revenue earned during the period from non-repayable sum of money awarded to an entity to carry out a specific purpose as provided in grant agreements.

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The amount of consideration recognized during the period for the milestone or milestones.

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Amount of revenue recognized from goods sold, services rendered, insurance premiums, or other activities that constitute an earning process. Includes, but is not limited to, investment and interest income before deduction of interest expense when recognized as a component of revenue, and sales and trading gain (loss).

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Summary of Revenue Recognized under Various Agreements (Detail) - USD ($) $ in Thousands	3 Months Ended				9 Months Ended		12 Months Ended
	Sep. 30, 2015	Dec. 31, 2014	Sep. 30, 2014	Mar. 31, 2014	Sep. 30, 2015	Sep. 30, 2014	Dec. 31, 2011
Product Information [Line Items]
Performance of research activities		$ 8,000		$ 5,400			$ 3,000
Total revenues	$ 1,188		$ 2,209		$ 3,365	$ 8,755
Grant revenue	359		414		608	2,546
Astra Zeneca
Product Information [Line Items]
Initial payment	60		180		186	540
Subsequent payment	223		675		697	2,025
Performance of research activities	546		309		1,347	1,741
Total revenues	829		1,164		2,230	4,306
National Institute of Allergy and Infectious Diseases
Product Information [Line Items]
Grant revenue			255			2,094
National Institutes of Health
Product Information [Line Items]
Grant revenue	$ 359		$ 159		$ 608	$ 452