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Component of Property and Equipment (Detail) - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2015
Dec. 31, 2014
Property Plant And Equipment [Line Items]    
Manufacturing equipment $ 6,880 $ 8,171
Lab equipment 6,096 6,473
Computer equipment 2,577 2,196
Furniture and fixtures 1,362 1,070
Leasehold improvements 5,768 5,690
Assets in progress 6,645 935
Property, Plant and Equipment, Gross 29,328 24,535
Less accumulated depreciation and amortization (15,524) (16,611)
Total $ 13,804 $ 7,924
Manufacturing Equipment | Minimum    
Property Plant And Equipment [Line Items]    
Estimated Useful Lives (In years) 5 years  
Manufacturing Equipment | Maximum    
Property Plant And Equipment [Line Items]    
Estimated Useful Lives (In years) 14 years  
Lab Equipment | Minimum    
Property Plant And Equipment [Line Items]    
Estimated Useful Lives (In years) 5 years  
Lab Equipment | Maximum    
Property Plant And Equipment [Line Items]    
Estimated Useful Lives (In years) 13 years  
Computer Equipment    
Property Plant And Equipment [Line Items]    
Estimated Useful Lives (In years) 3 years  
Furniture and Fixtures | Minimum    
Property Plant And Equipment [Line Items]    
Estimated Useful Lives (In years) 3 years  
Furniture and Fixtures | Maximum    
Property Plant And Equipment [Line Items]    
Estimated Useful Lives (In years) 13 years  
Leasehold Improvements | Minimum    
Property Plant And Equipment [Line Items]    
Estimated Useful Lives (In years) 5 years  
Leasehold Improvements | Maximum    
Property Plant And Equipment [Line Items]    
Estimated Useful Lives (In years) 8 years