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Computation of Basic and Diluted Earnings Per Share (Detail) - USD ($)
$ / shares in Units, shares in Thousands, $ in Thousands
3 Months Ended 12 Months Ended
Dec. 31, 2015
Sep. 30, 2015
Jun. 30, 2015
Mar. 31, 2015
Dec. 31, 2014
Sep. 30, 2014
Jun. 30, 2014
Mar. 31, 2014
Dec. 31, 2015
Dec. 31, 2014
Dec. 31, 2013
Basic and diluted net loss per share (in thousands, except per share amounts):                      
Net loss $ (26,862) $ (30,124) $ (23,591) $ (26,217) $ (22,286) $ (29,819) $ (24,777) $ (13,840) $ (106,794) $ (90,722) $ (66,720)
Preferred stock deemed dividend                     (8,469)
Net loss allocable to common stockholders $ (26,862) $ (30,124) $ (23,591) $ (26,217) $ (22,286) $ (29,819) $ (24,777) $ (13,840) $ (106,794) $ (90,722) $ (75,189)
Denominator for basic and diluted net loss per share allocable to common stockholders:                      
Weighted-average common shares outstanding 38,429 36,532 29,335 27,065 26,298 26,291 26,286 26,283 32,881 26,289 19,628
Net loss per share allocable to common stockholders - basic and diluted $ (0.70) $ (0.82) $ (0.80) $ (0.97) $ (0.85) $ (1.13) $ (0.94) $ (0.53) $ (3.25) $ (3.45) $ (3.83)
Outstanding securities not included in diluted net loss per share calculation (in thousands):                      
Outstanding securities not included in diluted net loss per share calculation                 3,086 7,422 7,293
Series B Convertible Preferred Stock                      
Outstanding securities not included in diluted net loss per share calculation (in thousands):                      
Outstanding securities not included in diluted net loss per share calculation                   4,343 4,343
Stock Options and Stock Awards                      
Outstanding securities not included in diluted net loss per share calculation (in thousands):                      
Outstanding securities not included in diluted net loss per share calculation                 3,086 1,998 1,704
Warrant                      
Outstanding securities not included in diluted net loss per share calculation (in thousands):                      
Outstanding securities not included in diluted net loss per share calculation                   1,081 1,246