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Selected Quarterly Financial Data (Detail) - USD ($)
$ / shares in Units, shares in Thousands, $ in Thousands
3 Months Ended 12 Months Ended
Dec. 31, 2015
Sep. 30, 2015
Jun. 30, 2015
Mar. 31, 2015
Dec. 31, 2014
Sep. 30, 2014
Jun. 30, 2014
Mar. 31, 2014
Dec. 31, 2015
Dec. 31, 2014
Dec. 31, 2013
Quarterly Financial Information Disclosure [Abstract]                      
Revenues $ 685 $ 1,188 $ 1,550 $ 627 $ 2,277 $ 2,209 $ 3,048 $ 3,498 $ 4,050 $ 11,032 $ 11,251
Net loss (26,862) (30,124) (23,591) (26,217) (22,286) (29,819) (24,777) (13,840) (106,794) (90,722) (66,720)
Net loss allocable to common stockholders $ (26,862) $ (30,124) $ (23,591) $ (26,217) $ (22,286) $ (29,819) $ (24,777) $ (13,840) $ (106,794) $ (90,722) $ (75,189)
Basic and diluted net loss per share allocable to common stockholders $ (0.70) $ (0.82) $ (0.80) $ (0.97) $ (0.85) $ (1.13) $ (0.94) $ (0.53) $ (3.25) $ (3.45) $ (3.83)
Weighted-average common shares outstanding 38,429 36,532 29,335 27,065 26,298 26,291 26,286 26,283 32,881 26,289 19,628