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Condensed Consolidated Statements of Operations (Unaudited) - USD ($) shares in Thousands, $ in Thousands	3 Months Ended
	Mar. 31, 2016	Mar. 31, 2015
Revenues:
Collaboration revenue	$ 895	$ 471
Grant revenue	39	148
Service and license revenue	8	8
Total revenues	942	627
Operating expenses:
Research and development	20,067	22,220
General and administrative	8,169	4,859
Total operating expenses	28,236	27,079
Loss from operations	(27,294)	(26,452)
Other income (expense):
Interest income	225	27
Interest expense		(247)
Other income, net	46	455
Net loss	$ (27,023)	$ (26,217)
Basic and diluted net loss per share	$ (0.70)	$ (0.97)
Weighted average shares used to compute basic and diluted net loss per share	38,472	27,065

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