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Income Taxes - Additional Information (Detail) - USD ($) | 12 Months Ended
--- | ---
Dec. 31, 2016 | Dec. 31, 2015 | Dec. 31, 2014
Income Tax Disclosure [Line Items] |  |  |
Income tax expense | $ 0 | $ 0 | $ 0
Increase (decrease) in valuation allowance | 36,400,000 | 36,200,000 | 27,800,000
Unrecognized tax benefits | 2,426,000 | $ 2,426,000 | $ 2,400,000
Unrecognized tax benefits would affect the effective tax rate | 0 |  |
Interest related to unrecognized tax benefits | 0 |  |
Penalties related to unrecognized tax benefits | 0 |  |
Accounting Standards Update 2016-09 |  |  |
Income Tax Disclosure [Line Items] |  |  |
Net operating loss carryforwards | 1,300,000 |  |
Federal |  |  |
Income Tax Disclosure [Line Items] |  |  |
Net operating loss carryforwards | $ 695,900,000 |  |
Federal | Minimum |  |  |
Income Tax Disclosure [Line Items] |  |  |
Net operating loss carryforwards, expiration year | 2018 |  |
Federal | Maximum |  |  |
Income Tax Disclosure [Line Items] |  |  |
Net operating loss carryforwards, expiration year | 2036 |  |
Federal | Research And Development Tax Credits |  |  |
Income Tax Disclosure [Line Items] |  |  |
Tax credit carryforward amount | $ 21,000,000 |  |
Federal | Research And Development Tax Credits | Minimum |  |  |
Income Tax Disclosure [Line Items] |  |  |
Tax credit carryforward amount, expiration year | 2018 |  |
Federal | Research And Development Tax Credits | Maximum |  |  |
Income Tax Disclosure [Line Items] |  |  |
Tax credit carryforward amount, expiration year | 2036 |  |
California and Other States |  |  |
Income Tax Disclosure [Line Items] |  |  |
Net operating loss carryforwards | $ 178,600,000 |  |
California and Other States | Minimum |  |  |
Income Tax Disclosure [Line Items] |  |  |
Net operating loss carryforwards, expiration year | 2017 |  |
California and Other States | Maximum |  |  |
Income Tax Disclosure [Line Items] |  |  |
Net operating loss carryforwards, expiration year | 2036 |  |
California State | Research And Development Tax Credits |  |  |
Income Tax Disclosure [Line Items] |  |  |
Tax credit carryforward amount | $ 15,900,000 |  |
Foreign |  |  |
Income Tax Disclosure [Line Items] |  |  |
Net operating loss carryforwards | $ 15,900,000 |  |

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- Definition Amount of current income tax expense (benefit) and deferred income tax expense (benefit) pertaining to continuing operations. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 740 -SubTopic 10 -Section 50 -Paragraph 9 -Subparagraph (a),(b) -URI http://asc.fasb.org/extlink&oid=65882285&loc=d3e32639-109319 Reference 2: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 235 -SubTopic 10 -Section S99 -Paragraph 1 -Subparagraph (SX 210.4-08.(h)) -URI http://asc.fasb.org/extlink&oid=26873400&loc=d3e23780-122690 Reference 3: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Glossary Income Tax Expense (or Benefit) -URI http://asc.fasb.org/extlink&oid=6515339 + Details
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