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Component of Property and Equipment (Detail) - USD ($)
$ in Thousands
 12 Months Ended
Dec. 31, 2016
Dec. 31, 2015
Property Plant And Equipment [Line Items]    
Manufacturing equipment $ 10,086 $ 6,880
Lab equipment 6,280 6,096
Computer equipment 4,010 2,577
Furniture and fixtures 1,566 1,362
Leasehold improvements 8,942 5,768
Assets in progress 2,298 6,645
Property, Plant and Equipment, Gross 33,182 29,328
Less accumulated depreciation and amortization (16,008) (15,524)
Total $ 17,174 $ 13,804
Manufacturing Equipment | Minimum    
Property Plant And Equipment [Line Items]    
Estimated Useful Lives (In years) 5 years  
Manufacturing Equipment | Maximum    
Property Plant And Equipment [Line Items]    
Estimated Useful Lives (In years) 14 years  
Lab Equipment | Minimum    
Property Plant And Equipment [Line Items]    
Estimated Useful Lives (In years) 5 years  
Lab Equipment | Maximum    
Property Plant And Equipment [Line Items]    
Estimated Useful Lives (In years) 13 years  
Computer Equipment    
Property Plant And Equipment [Line Items]    
Estimated Useful Lives (In years) 3 years  
Furniture and Fixtures | Minimum    
Property Plant And Equipment [Line Items]    
Estimated Useful Lives (In years) 3 years  
Furniture and Fixtures | Maximum    
Property Plant And Equipment [Line Items]    
Estimated Useful Lives (In years) 13 years  
Leasehold Improvements | Minimum    
Property Plant And Equipment [Line Items]    
Estimated Useful Lives (In years) 5 years  
Leasehold Improvements | Maximum    
Property Plant And Equipment [Line Items]    
Estimated Useful Lives (In years) 8 years