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Condensed Consolidated Statements of Operations (Unaudited) - USD ($) shares in Thousands, $ in Thousands	3 Months Ended
	Mar. 31, 2017	Mar. 31, 2016
Revenues:
Collaboration revenue		$ 895
Grant revenue	$ 148	39
Service and license revenue		8
Total revenues	148	942
Operating expenses:
Research and development	16,345	20,067
General and administrative	6,472	8,169
Restructuring	2,783
Total operating expenses	25,600	28,236
Loss from operations	(25,452)	(27,294)
Other income:
Interest income	145	225
Other income, net	20	46
Net loss	$ (25,287)	$ (27,023)
Basic and diluted net loss per share	$ (0.60)	$ (0.70)
Weighted average shares used to compute basic and diluted net loss per share	41,830	38,472

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