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Option Activity under Stock-Based Compensation Plans (Detail)
$ / shares in Units, shares in Thousands, $ in Thousands
 6 Months Ended
Jun. 30, 2017
USD ($)
$ / shares
shares
Shares Underlying Outstanding Options  
Beginning balance | shares 3,975
Options granted | shares 279
Ending balance | shares 3,751
Vested and expected to vest at June 30, 2017 | shares 3,741
Exercisable at June 30, 2017 | shares 2,290
Weighted-Average Exercise Price Per Share  
Beginning balance | $ / shares $ 21.38
Options granted | $ / shares 6.08
Ending balance | $ / shares 20.09
Vested and expected to vest at June 30, 2017 | $ / shares 20.10
Exercisable at June 30, 2017 | $ / shares $ 22.34
Weighted-Average Remaining Contractual Term (years)  
Balance at June 30, 2017 6 years 1 month 2 days
Vested and expected to vest at June 30, 2017 6 years 1 month 2 days
Exercisable at June 30, 2017 5 years 6 months 25 days
Aggregate Intrinsic Value  
Balance at June 30, 2017 | $ $ 1,136
Vested and expected to vest at June 30, 2017 | $ 1,136
Exercisable at June 30, 2017 | $ $ 151
Unvested  
Shares Underlying Outstanding Options  
Options cancelled | shares (310)
Weighted-Average Exercise Price Per Share  
Options cancelled | $ / shares $ 18.24
Vested  
Shares Underlying Outstanding Options  
Options cancelled | shares (193)
Weighted-Average Exercise Price Per Share  
Options cancelled | $ / shares $ 29.32