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Summary of Revenue Recognized under Various Agreements (Detail) - USD ($) $ in Thousands | 3 Months Ended | 12 Months Ended
--- | --- | ---
Dec. 31, 2017 | Sep. 30, 2017 | Jun. 30, 2017 | Mar. 31, 2017 | Dec. 31, 2016 | Sep. 30, 2016 | Jun. 30, 2016 | Mar. 31, 2016 | Dec. 31, 2017 | Dec. 31, 2016 | Dec. 31, 2015
Product Information [Line Items] |  |  |  |  |  |  |  |  |  |  |
Total revenues | $ 21 | $ 53 | $ 105 | $ 148 | $ 7,292 | $ 162 | $ 2,647 | $ 942 | $ 327 | $ 11,043 | $ 4,050
Astra Zeneca |  |  |  |  |  |  |  |  |  |  |
Product Information [Line Items] |  |  |  |  |  |  |  |  |  |  |
Initial and milestone payment |  |  |  |  |  |  |  |  |  | 7,722 | 238
Subsequent payment |  |  |  |  |  |  |  |  |  | 1,953 | 892
Performance of research activities |  |  |  |  | $ 7,200 |  |  |  |  | 103 | 1,635
Total revenues |  |  |  |  |  |  |  |  |  | $ 9,778 | $ 2,765

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- Definition Amount of deferred revenue recognized for transactions arising during the current reporting period. Deferred revenue is a liability as of the balance sheet date related to a revenue producing activity for which revenue has not yet been recognized. Generally, an Entity records deferred revenue when it receives consideration from a customer before achieving certain criteria that must be met for revenue to be recognized in conformity with GAAP. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 605 -SubTopic 10 -Section S99 -Paragraph 1 -Subparagraph (SAB TOPIC 13.A.4(a).Q1) -URI http://asc.fasb.org/extlink&oid=65893310&loc=d3e214044-122780 Reference 2: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 605 -SubTopic 10 -Section S99 -Paragraph 1 -Subparagraph (SAB Topic 13.A.3) -URI http://asc.fasb.org/extlink&oid=65893310&loc=d3e214044-122780 + Details
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