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Income Taxes - Additional Information (Detail) - USD ($) | 12 Months Ended
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Dec. 31, 2018 | Dec. 31, 2017 | Dec. 31, 2016 | Dec. 31, 2015
Income Tax Disclosure [Line Items] |  |  |  |
Income tax expense |  | $ 0 | $ 0 | $ 0
Increase (decrease) in valuation allowance |  | $ (108,800,000) | 36,400,000 | $ 36,200,000
Federal corporate income tax rate |  | 35.00% |  |
Tax act, net deferred tax assets |  | $ 87,000,000 |  |
Tax act, deferred tax assets valuation allowance |  | 87,000,000 |  |
Tax act, repatriation of undistributed earnings and profits of U.S. owned foreign corporations |  | 700,000 |  |
Unrecognized tax benefits |  | 1,229,000 | $ 2,426,000 |
Unrecognized tax benefits would affect the effective tax rate |  | 0 |  |
Interest related to unrecognized tax benefits |  | 0 |  |
Penalties related to unrecognized tax benefits |  | 0 |  |
Federal |  |  |  |
Income Tax Disclosure [Line Items] |  |  |  |
Net operating loss carryforwards |  | $ 629,100,000 |  |
Federal | Minimum |  |  |  |
Income Tax Disclosure [Line Items] |  |  |  |
Net operating loss carryforwards, expiration year |  | 2018 |  |
Federal | Maximum |  |  |  |
Income Tax Disclosure [Line Items] |  |  |  |
Net operating loss carryforwards, expiration year |  | 2037 |  |
Federal | Research And Development Tax Credits |  |  |  |
Income Tax Disclosure [Line Items] |  |  |  |
Tax credit carryforward amount |  | $ 16,900,000 |  |
Federal | Research And Development Tax Credits | Minimum |  |  |  |
Income Tax Disclosure [Line Items] |  |  |  |
Tax credit carryforward amount, expiration year |  | 2018 |  |
Federal | Research And Development Tax Credits | Maximum |  |  |  |
Income Tax Disclosure [Line Items] |  |  |  |
Tax credit carryforward amount, expiration year |  | 2037 |  |
California and Other States |  |  |  |
Income Tax Disclosure [Line Items] |  |  |  |
Net operating loss carryforwards |  | $ 168,400,000 |  |
California and Other States | Minimum |  |  |  |
Income Tax Disclosure [Line Items] |  |  |  |
Net operating loss carryforwards, expiration year |  | 2026 |  |
California and Other States | Maximum |  |  |  |
Income Tax Disclosure [Line Items] |  |  |  |
Net operating loss carryforwards, expiration year |  | 2037 |  |
California State | Research And Development Tax Credits |  |  |  |
Income Tax Disclosure [Line Items] |  |  |  |
Tax credit carryforward amount |  | $ 17,400,000 |  |
Foreign |  |  |  |
Income Tax Disclosure [Line Items] |  |  |  |
Net operating loss carryforwards |  | $ 15,500,000 |  |
New Corporate Tax Rate |  |  |  |
Income Tax Disclosure [Line Items] |  |  |  |
Federal corporate income tax rate | 21.00% |  |  |

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