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Income Taxes - Additional Information (Detail) - USD ($)
12 Months Ended
Dec. 31, 2018
Dec. 31, 2017
Dec. 31, 2016
Dec. 31, 2015
Income Tax Disclosure [Line Items]        
Income tax expense   $ 0 $ 0 $ 0
Increase (decrease) in valuation allowance   $ (108,800,000) 36,400,000 $ 36,200,000
Federal corporate income tax rate   35.00%    
Tax act, net deferred tax assets   $ 87,000,000    
Tax act, deferred tax assets valuation allowance   87,000,000    
Tax act, repatriation of undistributed earnings and profits of U.S. owned foreign corporations   700,000    
Unrecognized tax benefits   1,229,000 $ 2,426,000  
Unrecognized tax benefits would affect the effective tax rate   0    
Interest related to unrecognized tax benefits   0    
Penalties related to unrecognized tax benefits   0    
Federal        
Income Tax Disclosure [Line Items]        
Net operating loss carryforwards   $ 629,100,000    
Federal | Minimum        
Income Tax Disclosure [Line Items]        
Net operating loss carryforwards, expiration year   2018    
Federal | Maximum        
Income Tax Disclosure [Line Items]        
Net operating loss carryforwards, expiration year   2037    
Federal | Research And Development Tax Credits        
Income Tax Disclosure [Line Items]        
Tax credit carryforward amount   $ 16,900,000    
Federal | Research And Development Tax Credits | Minimum        
Income Tax Disclosure [Line Items]        
Tax credit carryforward amount, expiration year   2018    
Federal | Research And Development Tax Credits | Maximum        
Income Tax Disclosure [Line Items]        
Tax credit carryforward amount, expiration year   2037    
California and Other States        
Income Tax Disclosure [Line Items]        
Net operating loss carryforwards   $ 168,400,000    
California and Other States | Minimum        
Income Tax Disclosure [Line Items]        
Net operating loss carryforwards, expiration year   2026    
California and Other States | Maximum        
Income Tax Disclosure [Line Items]        
Net operating loss carryforwards, expiration year   2037    
California State | Research And Development Tax Credits        
Income Tax Disclosure [Line Items]        
Tax credit carryforward amount   $ 17,400,000    
Foreign        
Income Tax Disclosure [Line Items]        
Net operating loss carryforwards   $ 15,500,000    
New Corporate Tax Rate        
Income Tax Disclosure [Line Items]        
Federal corporate income tax rate 21.00%