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Summary of Cash, Cash Equivalents and Marketable Securities (Detail) - USD ($) $ in Thousands | Mar. 31, 2018 | Dec. 31, 2017
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Cash Cash Equivalents And Marketable Securities [Line Items] |  |
Amortized Cost | $ 250,881 | $ 191,934
Unrealized Gains | 6 |
Unrealized Losses | (107) | (80)
Estimated Fair Value | 250,780 | 191,854
Cash and Cash Equivalents |  |
Cash Cash Equivalents And Marketable Securities [Line Items] |  |
Amortized Cost | 36,067 | 26,584
Estimated Fair Value | 36,067 | 26,584
Marketable Securities Available-for-Sale |  |
Cash Cash Equivalents And Marketable Securities [Line Items] |  |
Amortized Cost | 214,814 | 165,350
Unrealized Gains | 6 |
Unrealized Losses | (107) | (80)
Estimated Fair Value | 214,713 | 165,270
Cash | Cash and Cash Equivalents |  |
Cash Cash Equivalents And Marketable Securities [Line Items] |  |
Amortized Cost | 1,908 | 4,041
Estimated Fair Value | 1,908 | 4,041
Money Market Funds | Cash and Cash Equivalents |  |
Cash Cash Equivalents And Marketable Securities [Line Items] |  |
Amortized Cost | 25,923 | 22,543
Estimated Fair Value | 25,923 | 22,543
U.S. Treasuries | Cash and Cash Equivalents |  |
Cash Cash Equivalents And Marketable Securities [Line Items] |  |
Amortized Cost | 4,000 |
Estimated Fair Value | 4,000 |
U.S. Treasuries | Marketable Securities Available-for-Sale |  |
Cash Cash Equivalents And Marketable Securities [Line Items] |  |
Amortized Cost | 45,218 | 45,559
Unrealized Losses | (12) | (25)
Estimated Fair Value | 45,206 | 45,534
Corporate Debt Securities | Cash and Cash Equivalents |  |
Cash Cash Equivalents And Marketable Securities [Line Items] |  |
Amortized Cost | 4,236 |
Estimated Fair Value | 4,236 |
Corporate Debt Securities | Marketable Securities Available-for-Sale |  |
Cash Cash Equivalents And Marketable Securities [Line Items] |  |
Amortized Cost | 114,931 | 32,931
Unrealized Gains | 5 |
Unrealized Losses | (73) | (15)
Estimated Fair Value | 114,863 | 32,916
U.S. Government Agency Securities | Marketable Securities Available-for-Sale |  |
Cash Cash Equivalents And Marketable Securities [Line Items] |  |
Amortized Cost | 54,665 | 86,860
Unrealized Gains | 1 |
Unrealized Losses | (22) | (40)
Estimated Fair Value | $ 54,644 | $ 86,820

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- Definition Amount of investment in debt and equity securities categorized neither as held-to-maturity nor trading. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 320 -SubTopic 10 -Section 25 -Paragraph 1 -Subparagraph (b) -URI http://asc.fasb.org/extlink&oid=75030427&loc=d3e22054-111558 Reference 2: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 320 -SubTopic 10 -Section 50 -Paragraph 5 -Subparagraph (aa) -URI http://asc.fasb.org/extlink&oid=82897076&loc=d3e27232-111563 Reference 3: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 320 -SubTopic 10 -Section 45 -Paragraph 1 -URI http://asc.fasb.org/extlink&oid=82896770&loc=d3e26610-111562 + Details
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