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Collaborative Research, Development and License Agreements - Additional Information (Detail) |  | 1 Months Ended | 3 Months Ended
--- | --- | --- | ---
Mar. 31, 2018 USD ($) | Feb. 28, 2018 USD ($) Installment | Jan. 31, 2018 USD ($) | Mar. 31, 2020 USD ($) | Mar. 31, 2019 USD ($) | Mar. 31, 2018 USD ($)
Merck, Sharp & Dohme Corp. | Sublicense Agreement |  |  |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |  |  |
Aggregate amount payable to acquire intangible assets |  | $ 21,000,000 |  |  |  |
Number of installments | Installment |  | 3 |  |  |  |
Payment upon obligation |  | $ 7,000,000 |  |  |  |
Intangible assets |  | $ 19,800,000 |  |  |  |
Merck, Sharp & Dohme Corp. | Sublicense Agreement | Scenario, Forecast |  |  |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |  |  |
Payment upon obligation |  |  |  | $ 7,000,000 | $ 7,000,000 |
Coley Pharmaceutical Group, Inc. |  |  |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |  |  |
Agreement termination date |  |  |  |  |  | 2018-02
Amortization of intangible assets | $ 2,500,000 |  |  |  |  |
Coley Pharmaceutical Group, Inc. | Intangible Assets |  |  |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |  |  |
Payment for regulatory milestones recorded as intangible asset |  |  | $ 2,500,000 |  |  |
Maximum |  |  |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |  |  |
Additional milestone payments eligible to be received based on achievement of certain development and regulatory objectives | $ 100,000,000 |  |  |  |  | $ 100,000,000

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