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Organization and Summary of Significant Accounting Policies - Additional Information (Detail)
1 Months Ended 6 Months Ended
Nov. 30, 2017
Jun. 30, 2018
USD ($)
Segment
Jun. 30, 2017
USD ($)
Feb. 28, 2018
USD ($)
Feb. 20, 2018
USD ($)
Organization Consolidation And Presentation Of Financial Statements Disclosure [Line Items]          
Number of operating segment | Segment   1      
Cash, cash equivalents and marketable securities   $ 216,000,000      
Maximum borrowing capacity       $ 175,000,000  
Cash used in operating activities   63,799,000 $ 42,642,000    
Impairment of Intangible assets   $ 0      
Federal corporate income tax rate   21.00%      
Maximum          
Organization Consolidation And Presentation Of Financial Statements Disclosure [Line Items]          
Expected period of payment to be received   1 year      
Provisional amounts expected measurement period   1 year      
Patent License Agreements          
Organization Consolidation And Presentation Of Financial Statements Disclosure [Line Items]          
Paid fees under patent license agreements   $ 9,500,000      
CRG Servicing LLC          
Organization Consolidation And Presentation Of Financial Statements Disclosure [Line Items]          
Maximum borrowing capacity         $ 175,000,000
Current borrowing capacity         100,000,000
Additional borrowing capacity         $ 75,000,000
HEPLISAV-B®          
Organization Consolidation And Presentation Of Financial Statements Disclosure [Line Items]          
Minimum age approved for vaccine prevention of infection caused 18 years