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Organization and Summary of Significant Accounting Policies - Additional Information (Detail) | 1 Months Ended | 9 Months Ended |
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Nov. 30, 2017 | Sep. 30, 2018 USD ($) Segment | Sep. 30, 2017 USD ($) | Feb. 20, 2018 USD ($)
Organization Consolidation And Presentation Of Financial Statements Disclosure [Line Items] |  |  |  |
Number of operating segment | Segment |  | 1 |  |
Cash, cash equivalents and marketable securities |  | $ 180,200,000 |  |
Cash used in operating activities |  | 97,671,000 | $ 59,769,000 |
Impairment of Intangible assets |  | $ 0 |  |
Federal corporate income tax rate |  | 21.00% |  |
Maximum |  |  |  |
Organization Consolidation And Presentation Of Financial Statements Disclosure [Line Items] |  |  |  |
Expected period of payment to be received |  | 1 year |  |
Provisional amounts expected measurement period |  | 1 year |  |
Patent License Agreements |  |  |  |
Organization Consolidation And Presentation Of Financial Statements Disclosure [Line Items] |  |  |  |
Paid fees under patent license agreements |  | $ 11,000,000 |  |
CRG Servicing LLC |  |  |  |
Organization Consolidation And Presentation Of Financial Statements Disclosure [Line Items] |  |  |  |
Additional borrowing capacity |  |  |  | $ 75,000,000
Loan agreement market capitalization requirement |  |  |  | $ 300,000,000
HEPLISAV-B® |  |  |  |
Organization Consolidation And Presentation Of Financial Statements Disclosure [Line Items] |  |  |  |
Minimum age approved for vaccine prevention of infection caused | 18 years |  |  |

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- Definition Cash includes currency on hand as well as demand deposits with banks or financial institutions. It also includes other kinds of accounts that have the general characteristics of demand deposits in that the customer may deposit additional funds at any time and effectively may withdraw funds at any time without prior notice or penalty. Cash equivalents, excluding items classified as marketable securities, include short-term, highly liquid Investments that are both readily convertible to known amounts of cash, and so near their maturity that they present minimal risk of changes in value because of changes in interest rates. Generally, only investments with original maturities of three months or less qualify under that definition. Original maturity means original maturity to the entity holding the investment. For example, both a three-month US Treasury bill and a three-year Treasury note purchased three months from maturity qualify as cash equivalents. However, a Treasury note purchased three years ago does not become a cash equivalent when its remaining maturity is three months. Short-term investments, exclusive of cash equivalents, generally consist of marketable securities intended to be sold within one year (or the normal operating cycle if longer) and may include trading securities, available-for-sale securities, or held-to-maturity securities (if maturing within one year), as applicable. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 210 -SubTopic 10 -Section S99 -Paragraph 1 -Subparagraph (SX 210.5-02.1) -URI http://asc.fasb.org/extlink&oid=6877327&loc=d3e13212-122682 + Details
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