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Revenue Recognition - Summary of Product Revenue Allowance and Reserve Categories (Detail) - HEPLISAV-B® $ in Thousands	9 Months Ended
	Sep. 30, 2018 USD ($)
Product Revenue Allowance and Revenue Categories [Line Items]
Provision related to current period sales	$ 2,098
Credit or payments made during the period	(739)
Balance at September 30, 2018	1,359
Chargebacks, Discounts and Other Fees
Product Revenue Allowance and Revenue Categories [Line Items]
Provision related to current period sales	1,849
Credit or payments made during the period	(739)
Balance at September 30, 2018	1,110
Returns
Product Revenue Allowance and Revenue Categories [Line Items]
Provision related to current period sales	249
Balance at September 30, 2018	$ 249