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Intangible Assets, Net - Additional Information (Detail) - USD ($)
 12 Months Ended
Dec. 31, 2018
Dec. 31, 2017
Finite Lived Intangible Assets [Line Items]    
Cost of sales - amortization of intangible assets $ 10,862,000 $ 1,194,000
Estimated remaining useful life of intangible assets 16 months  
Impairment of intangible assets $ 0  
Merck    
Finite Lived Intangible Assets [Line Items]    
Amortization of intangible assets 8,100,000  
GlaxoSmithKline Biologicals SA    
Finite Lived Intangible Assets [Line Items]    
Amortization of intangible assets 1,500,000  
Coley Pharmaceutical Group, Inc.    
Finite Lived Intangible Assets [Line Items]    
Amortization of intangible assets $ 1,300,000