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Revenue Recognition - Summary of Product Revenue Allowance and Reserve Categories (Detail) - HEPLISAV-B® $ in Thousands	12 Months Ended
	Dec. 31, 2018 USD ($)
Product Revenue Allowance and Revenue Categories [Line Items]
Provision related to current period sales	$ 4,582
Credit or payments made during the period	(2,277)
Balance at December 31, 2018	2,305
Chargebacks, Discounts and Other Fees
Product Revenue Allowance and Revenue Categories [Line Items]
Provision related to current period sales	4,012
Credit or payments made during the period	(2,276)
Balance at December 31, 2018	1,736
Returns
Product Revenue Allowance and Revenue Categories [Line Items]
Provision related to current period sales	570
Credit or payments made during the period	(1)
Balance at December 31, 2018	$ 569