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Selected Quarterly Financial Data (Detail) - USD ($) $ / shares in Units, shares in Thousands, $ in Thousands	3 Months Ended								12 Months Ended
	Dec. 31, 2018	Sep. 30, 2018	Jun. 30, 2018	Mar. 31, 2018	Dec. 31, 2017	Sep. 30, 2017	Jun. 30, 2017	Mar. 31, 2017	Dec. 31, 2018	Dec. 31, 2017	Dec. 31, 2016
Quarterly Financial Information Disclosure [Abstract]
Total revenues	$ 5,318	$ 1,461	$ 1,254	$ 165	$ 21	$ 53	$ 105	$ 148	$ 8,198	$ 327	$ 11,043
Net loss	$ (39,969)	$ (40,528)	$ (39,444)	$ (38,958)	$ (27,421)	$ (22,128)	$ (20,318)	$ (25,287)	$ (158,899)	$ (95,154)	$ (112,444)
Basic and diluted net loss per share	$ (0.64)	$ (0.65)	$ (0.63)	$ (0.63)	$ (0.45)	$ (0.38)	$ (0.41)	$ (0.60)	$ (2.55)	$ (1.81)	$ (2.92)
Shares used to compute basic and diluted net loss per share	62,694	62,650	62,346	61,744	61,007	57,650	49,700	41,830	62,362	52,613	38,506

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- Definition

The amount of net income or loss for the period per each share in instances when basic and diluted earnings per share are the same amount and reported as a single line item on the face of the financial statements. Basic earnings per share is the amount of net income or loss for the period per each share of common stock or unit outstanding during the reporting period. Diluted earnings per share includes the amount of net income or loss for the period available to each share of common stock or common unit outstanding during the reporting period and to each share or unit that would have been outstanding assuming the issuance of common shares or units for all dilutive potential common shares or units outstanding during the reporting period.

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The portion of profit or loss for the period, net of income taxes, which is attributable to the parent.

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