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Condensed Consolidated Statements of Stockholders' Equity - USD ($)
shares in Thousands, $ in Thousands
Total
Common Stock
Additional Paid-in Capital
Accumulated Other Comprehensive (Loss) Income
Accumulated Deficit
Beginning Balances at Dec. 31, 2017 $ 199,549 $ 62 $ 1,107,693 $ (881) $ (907,325)
Beginning Balances (in shares) at Dec. 31, 2017   61,533      
Issuance (withholding) of common stock upon exercise of stock options and restricted stock awards, net (426)   (426)    
Issuance (withholding) of common stock upon exercise of stock options and restricted stock awards, net (in shares)   663      
Issuance of common stock under Employee Stock Purchase Plan 255   255    
Issuance of common stock under Employee Stock Purchase Plan (in shares)   58      
Stock compensation expense 4,799   4,799    
Total other comprehensive income (loss) 668     668  
Net loss (38,958)       (38,958)
Ending Balances at Mar. 31, 2018 165,887 $ 62 1,112,321 (213) (946,283)
Ending Balances (in shares) at Mar. 31, 2018   62,254      
Beginning Balances at Dec. 31, 2018 63,065 $ 63 1,131,241 (2,015) (1,066,224)
Beginning Balances (in shares) at Dec. 31, 2018   62,862      
Issuance (withholding) of common stock upon exercise of stock options and restricted stock awards, net (18)   (18)    
Issuance (withholding) of common stock upon exercise of stock options and restricted stock awards, net (in shares)   740      
Issuance of common stock under Employee Stock Purchase Plan 407   407    
Issuance of common stock under Employee Stock Purchase Plan (in shares)   75      
Issuance of common stock, net of issuance costs 13,623 $ 2 13,621    
Issuance of common stock, net of issuance costs (in shares)   1,343      
Stock compensation expense 6,170   6,170    
Total other comprehensive income (loss) (416)     (416)  
Net loss (39,672)       (39,672)
Ending Balances at Mar. 31, 2019 $ 43,159 $ 65 $ 1,151,421 $ (2,431) $ (1,105,896)
Ending Balances (in shares) at Mar. 31, 2019   65,020