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Condensed Consolidated Statements of Cash Flows (Unaudited) - USD ($)
$ in Thousands
 3 Months Ended
Mar. 31, 2019
Mar. 31, 2018
Operating activities    
Net loss $ (39,672) $ (38,958)
Adjustments to reconcile net loss to net cash used in operating activities:    
Depreciation and amortization 1,702 823
Amortization of right-of-use assets 1,302  
Accretion of discounts on marketable securities (323) (176)
Stock compensation expense 6,170 4,799
Cost of sales - amortization of intangible assets 2,273 2,417
Non-cash interest expense 814 348
Changes in operating assets and liabilities:    
Accounts and other receivables (2,087) 91
Inventories, net (8,547) (238)
Prepaid expenses and other current assets 154 394
Other assets 1,872 3
Accounts payable 4,424 349
Lease liabilities (106)  
Accrued liabilities and other liabilities (7,878) 276
Net cash used in operating activities (39,902) (29,872)
Investing activities    
Acquisition of technology licenses (7,000) (9,500)
Purchases of marketable securities (29,205) (141,103)
Proceeds from maturities of marketable securities 54,700 91,815
Purchases of property and equipment, net (3,882) (897)
Net cash provided by (used in) investing activities 14,613 (59,685)
Financing activities    
Proceeds from long-term debt, net 74,250 99,000
Proceeds from issuance of common stock, net 13,623  
Tax withholding from exercise of stock options and restricted stock awards, net (18) (426)
Proceeds from Employee Stock Purchase Plan 407 255
Net cash provided by financing activities 88,262 98,829
Effect of exchange rate changes on cash, cash equivalents and restricted cash (192) 217
Net increase in cash, cash equivalents and restricted cash 62,781 9,489
Cash, cash equivalents and restricted cash at beginning of period 49,967 27,213
Cash, cash equivalents and restricted cash at end of period 112,748 36,702
Supplemental disclosure of cash flow information    
Cash paid during the period for interest 1,940 813
Non-cash investing and financing activities:    
Disposal of fully depreciated property and equipment 851 37
Non-cash acquisition of technology license   $ 12,773
Right-of-use assets obtained in exchange for operating lease liabilities $ 34,807