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Option Activity under Stock-Based Compensation Plans (Detail)
$ / shares in Units, shares in Thousands, $ in Thousands
 6 Months Ended
Jun. 30, 2019
USD ($)
$ / shares
shares
Shares Underlying Outstanding Options  
Beginning balance | shares 5,750
Options granted | shares 2,925
Options exercised | shares (10)
Ending balance | shares 8,418
Vested and expected to vest at June 30, 2019 | shares 7,970
Exercisable at June 30, 2019 | shares 3,893
Weighted-Average Exercise Price Per Share  
Beginning balance | $ / shares $ 18.20
Options granted | $ / shares 7.04
Options exercised | $ / shares 5.75
Ending balance | $ / shares 14.42
Vested and expected to vest at June 30, 2019 | $ / shares 14.75
Exercisable at June 30, 2019 | $ / shares $ 19.14
Weighted-Average Remaining Contractual Term (years)  
Balance at June 30, 2019 5 years 1 month 17 days
Vested and expected to vest at June 30, 2019 5 years 25 days
Exercisable at June 30, 2019 4 years 2 months 1 day
Aggregate Intrinsic Value  
Balance at June 30, 2019 | $ $ 199
Vested and expected to vest at June 30, 2019 | $ $ 173
Unvested  
Shares Underlying Outstanding Options  
Options cancelled | shares (142)
Weighted-Average Exercise Price Per Share  
Options cancelled | $ / shares $ 13.98
Vested  
Shares Underlying Outstanding Options  
Options cancelled | shares (105)
Weighted-Average Exercise Price Per Share  
Options cancelled | $ / shares $ 17.55