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Intangible Assets, Net - Additional Information (Detail) - USD ($)	12 Months Ended
	Dec. 31, 2019	Dec. 31, 2018	Dec. 31, 2017
Finite Lived Intangible Assets [Line Items]
Cost of sales - amortization of intangible assets	$ 9,217,000	$ 10,862,000	$ 1,194,000
Impairment of intangible assets	0	0
Merck
Finite Lived Intangible Assets [Line Items]
Cost of sales - amortization of intangible assets	$ 9,200,000	8,100,000
GlaxoSmithKline Biologicals SA
Finite Lived Intangible Assets [Line Items]
Cost of sales - amortization of intangible assets		1,500,000
Coley Pharmaceutical Group, Inc.
Finite Lived Intangible Assets [Line Items]
Cost of sales - amortization of intangible assets		$ 1,300,000	$ 1,200,000

X

- Definition

Amount of expense for allocation of cost of intangible asset over its useful life directly used in production of good and rendering of service.

+ References

Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 220
-SubTopic 10
-Section S99
-Paragraph 2
-Subparagraph (SX 210.5-03(b)(2))
-URI http://asc.fasb.org/extlink&oid=116634182&loc=SL114868664-224227

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- Definition

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+ References

No definition available.

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- Definition

The amount of impairment loss recognized in the period resulting from the write-down of the carrying amount of a finite-lived intangible asset to fair value.

+ References

Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 230
-SubTopic 10
-Section 45
-Paragraph 28
-Subparagraph (b)
-URI http://asc.fasb.org/extlink&oid=118932676&loc=d3e3602-108585

Reference 2: http://www.xbrl.org/2009/role/commonPracticeRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 350
-SubTopic 30
-Section 50
-Paragraph 3
-Subparagraph (b)
-URI http://asc.fasb.org/extlink&oid=66006027&loc=d3e16373-109275

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