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Difference between Consolidated Income Tax Benefit and Amount Computed by Federal Statutory Income Tax Rate (Detail) - USD ($)	12 Months Ended
	Dec. 31, 2019	Dec. 31, 2018	Dec. 31, 2017
Income Tax Disclosure [Abstract]
Income tax benefit at federal statutory rate	$ (32,046,000)	$ (33,366,000)	$ (32,352,000)
State tax	(3,153,000)	(5,591,000)	(4,482,000)
Business credits	(1,757,000)	(3,065,000)	(1,960,000)
Uncertain tax positions	5,426,000
Deferred compensation charges	4,600,000	(1,165,000)	3,823,000
Change in valuation allowance	22,715,000	43,134,000	(109,165,000)
Rate change			86,943,000
Net operating loss and tax credit limitation			56,962,000
Section 162(m) limitation	2,439,000
Mark-to-market of warrants	1,575,000
Other	201,000	53,000	231,000
Total income tax expense	$ 0	$ 0	$ 0

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