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Common Stock, Preferred Stock and Warrants - Additional Information (Detail) - USD ($)
 1 Months Ended 3 Months Ended 6 Months Ended
Aug. 06, 2020
Nov. 03, 2017
May 31, 2020
Aug. 31, 2019
Jun. 30, 2020
Jun. 30, 2019
Jun. 30, 2020
Jun. 30, 2019
May 28, 2020
May 27, 2020
Mar. 11, 2020
Dec. 31, 2019
Aug. 12, 2019
Class Of Stock [Line Items]                          
Common stock, par value       $ 0.001 $ 0.001   $ 0.001   $ 0.001     $ 0.001  
Common stock, shares authorized         278,000,000   278,000,000   278,000,000 139,000,000   139,000,000  
Common stock, shares outstanding         109,503,242   109,503,242         83,871,000  
Issuance of common stock and preferred stock (in shares)       18,525,000                  
Preferred stock, par value         $ 0.001   $ 0.001         $ 0.001  
Net cash proceeds received             $ 107,697,000 $ 13,949,000          
Change in fair value of warrant liability         $ 25,655,000   $ 17,045,000            
Common Stock                          
Class Of Stock [Line Items]                          
Issuance of common stock and preferred stock (in shares)         21,197,000 44,000 24,106,000 1,387,000          
Stock Issued During Period, Shares, Conversion of Convertible Securities         700,000   700,000            
Warrants                          
Class Of Stock [Line Items]                          
Fair value of derivative liability         $ 31,900,000   $ 31,900,000           $ 7,400,000
Warrants | Other Income, Net                          
Class Of Stock [Line Items]                          
Change in fair value of warrant liability         $ 25,700,000   $ 17,000,000.0            
Bain Life Sciences                          
Class Of Stock [Line Items]                          
Net cash proceeds received from issuance or sale of equity       $ 35,000,000.0                  
Bain Capital Life Sciences Fund, L.P                          
Class Of Stock [Line Items]                          
Issuance of common stock and preferred stock (in shares)       6,826,266                  
Number of common stock allowed to purchase       2,645,566                  
Net cash proceeds received from issuance or sale of equity       $ 31,700,000                  
BCIP Life Sciences Associates, L.P                          
Class Of Stock [Line Items]                          
Issuance of common stock and preferred stock (in shares)       698,734                  
Number of common stock allowed to purchase       270,684                  
Net cash proceeds received from issuance or sale of equity       $ 3,200,000                  
Public Offering                          
Class Of Stock [Line Items]                          
Common stock, par value     $ 0.001                    
Issuance of common stock and preferred stock (in shares)     2,100,000                    
Number of common stock allowed to purchase       0.25                  
Combined price of common stock and warrant     $ 5.00 $ 3.00                  
Net cash proceeds received from issuance or sale of equity     $ 75,400,000 $ 65,600,000                  
Payment of issuance costs       $ 4,500,000                  
Public Offering | Bain Capital Life Sciences Fund, L.P                          
Class Of Stock [Line Items]                          
Issuance of common stock and preferred stock (in shares)     1,000,000                    
2017 ATM Agreement                          
Class Of Stock [Line Items]                          
Issuance of common stock and preferred stock (in shares)             8,005,467            
Net cash proceeds received             $ 32,300,000            
Remaining proceeds from common stock, under sales agreement             $ 78,900,000            
Series B Convertible Preferred Stock                          
Class Of Stock [Line Items]                          
Issuance of common stock and preferred stock (in shares)       4,840                  
Preferred stock, par value       $ 0.001                  
Preferred stock, shares outstanding         4,140   4,140         5,000  
Issuance of common stock and preferred stock (in shares)         700                
Preferred stock deemed dividend             $ 3,300,000            
Series B Convertible Preferred Stock | Common Stock                          
Class Of Stock [Line Items]                          
Number of common stock allowed to purchase         1,000   1,000            
Series B Convertible Preferred Stock | Bain Capital Life Sciences Fund, L.P                          
Class Of Stock [Line Items]                          
Issuance of common stock and preferred stock (in shares)       3,756                  
Series B Convertible Preferred Stock | BCIP Life Sciences Associates, L.P                          
Class Of Stock [Line Items]                          
Issuance of common stock and preferred stock (in shares)       384                  
Series B Convertible Preferred Stock | Public Offering                          
Class Of Stock [Line Items]                          
Number of common stock allowed to purchase       250                  
Combined price of preferred stock and warrant       $ 3,000                  
Series C Convertible Preferred Stock | Bain Life Sciences | Common Stock                          
Class Of Stock [Line Items]                          
Number of common stock allowed to purchase                     1,000    
Conversion price per share                     $ 4.50    
Maximum | Subsequent Event                          
Class Of Stock [Line Items]                          
Common stock sales agreement aggregate sales proceeds $ 150,000,000                        
Maximum | Warrants                          
Class Of Stock [Line Items]                          
Percentage of common stock held not to exceed for warrant exercises             19.99%            
Maximum | Public Offering                          
Class Of Stock [Line Items]                          
Issuance of common stock and preferred stock (in shares)     16,100,000                    
Warrant issued       5,841,250                  
Maximum | 2017 ATM Agreement                          
Class Of Stock [Line Items]                          
Common stock sales agreement aggregate sales proceeds   $ 150,000,000                      
Commission on gross sales proceeds of common stock   3.00%                      
Maximum | Series B Convertible Preferred Stock                          
Class Of Stock [Line Items]                          
Percentage of common stock held not to exceed for warrant exercises             19.99%            
Minimum | Warrants                          
Class Of Stock [Line Items]                          
Percentage of common stock to be held for exercise of warrants             4.99%            
Minimum | Series B Convertible Preferred Stock                          
Class Of Stock [Line Items]                          
Percentage of common stock to be held for conversion             4.99%