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Equity Plans and Stock-Based Compensation - Stock-Based Compensation Expense (Detail) - USD ($) $ in Thousands | 3 Months Ended | 9 Months Ended
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Sep. 30, 2020 | Sep. 30, 2019 | Sep. 30, 2020 | Sep. 30, 2019
Deferred Compensation Arrangement With Individual Share Based Payments [Line Items] |  |  |  |
Stock-based compensation expense | $ 4,102 | $ 4,748 | $ 9,968 | $ 20,267
Research and Development |  |  |  |
Deferred Compensation Arrangement With Individual Share Based Payments [Line Items] |  |  |  |
Stock-based compensation expense | 778 | 1,661 | (21) | 5,817
Selling, General and Administrative |  |  |  |
Deferred Compensation Arrangement With Individual Share Based Payments [Line Items] |  |  |  |
Stock-based compensation expense | 2,504 | 2,278 | 7,437 | 7,828
Restructuring |  |  |  |
Deferred Compensation Arrangement With Individual Share Based Payments [Line Items] |  |  |  |
Stock-based compensation expense |  |  |  | 4,122
Cost of Sales - Product |  |  |  |
Deferred Compensation Arrangement With Individual Share Based Payments [Line Items] |  |  |  |
Stock-based compensation expense | 137 | 189 | 452 | 819
Inventory |  |  |  |
Deferred Compensation Arrangement With Individual Share Based Payments [Line Items] |  |  |  |
Stock-based compensation expense | $ 683 | $ 620 | $ 2,100 | $ 1,681

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