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Common Stock, Preferred Stock and Warrants - Additional Information (Detail) - USD ($)
 1 Months Ended 3 Months Ended 9 Months Ended
Aug. 06, 2020
Nov. 03, 2017
May 31, 2020
Aug. 31, 2019
Sep. 30, 2020
Jun. 30, 2020
Sep. 30, 2019
Sep. 30, 2020
Sep. 30, 2019
May 28, 2020
May 27, 2020
Mar. 11, 2020
Dec. 31, 2019
Aug. 12, 2019
Class Of Stock [Line Items]                            
Common stock, par value       $ 0.001 $ 0.001     $ 0.001   $ 0.001     $ 0.001  
Common stock, shares authorized         278,000,000     278,000,000   278,000,000 139,000,000   139,000,000  
Common stock, shares outstanding         110,172,859     110,172,859         83,871,000  
Issuance of common stock and preferred stock (in shares)       18,525,000                    
Preferred stock, par value         $ 0.001     $ 0.001         $ 0.001  
Common Stock Shares Sold               8,005,467            
Received Net Cash Proceeds               $ 32,300,000            
Net cash proceeds received               $ 108,537,000 $ 65,948,000          
Preferred stock, shares outstanding         4,140     4,140            
Preferred stock deemed dividend             $ 3,267,000   3,267,000          
Change in fair value of warrant liability         $ (21,245,000)     $ (4,200,000) $ 234,000          
Common Stock                            
Class Of Stock [Line Items]                            
Issuance of common stock and preferred stock (in shares)         109,000   18,525,000 24,215,000 19,912,000          
Number of common stock allowed to purchase         1,000     1,000       1,000    
Conversion price per share                       $ 4.50    
Stock Issued During Period, Shares, Conversion of Convertible Securities           700,000   700,000            
Warrants                            
Class Of Stock [Line Items]                            
Fair value of derivative liability         $ 10,700,000     $ 10,700,000           $ 7,400,000
Warrants | Other Income, Net                            
Class Of Stock [Line Items]                            
Change in fair value of warrant liability         $ 21,200,000     $ 4,200,000            
Bain Life Sciences                            
Class Of Stock [Line Items]                            
Net cash proceeds received from issuance or sale of equity       $ 35,000,000.0                    
Bain Capital Life Sciences Fund, L.P                            
Class Of Stock [Line Items]                            
Issuance of common stock and preferred stock (in shares)       6,826,266                    
Number of common stock allowed to purchase       2,645,566                    
Net cash proceeds received from issuance or sale of equity       $ 31,700,000                    
BCIP Life Sciences Associates, L.P                            
Class Of Stock [Line Items]                            
Issuance of common stock and preferred stock (in shares)       698,734                    
Number of common stock allowed to purchase       270,684                    
Net cash proceeds received from issuance or sale of equity       $ 3,200,000                    
Offering                            
Class Of Stock [Line Items]                            
Common stock, par value     $ 0.001                      
Issuance of common stock and preferred stock (in shares)     2,100,000                      
Number of common stock allowed to purchase       0.25                    
Combined price of common stock and warrant       $ 3.00                    
Net cash proceeds received from issuance or sale of equity     $ 75,400,000 $ 65,600,000                    
Payment of issuance costs       $ 4,500,000                    
Price of common stock     $ 5.00                      
Offering | Bain Capital Life Sciences Fund, L.P                            
Class Of Stock [Line Items]                            
Issuance of common stock and preferred stock (in shares)     1,000,000                      
2017 ATM Agreement                            
Class Of Stock [Line Items]                            
Issuance of common stock and preferred stock (in shares)               109,176            
Net cash proceeds received               $ 800,000            
Remaining proceeds from common stock, under sales agreement               $ 149,100,000            
Series B Convertible Preferred Stock                            
Class Of Stock [Line Items]                            
Issuance of common stock and preferred stock (in shares)       4,840                    
Preferred stock, par value       $ 0.001                    
Preferred stock, shares outstanding         4,000     4,000         5,000  
Issuance of common stock and preferred stock (in shares)           700                
Preferred stock deemed dividend               $ 3,300,000            
Series B Convertible Preferred Stock | Bain Capital Life Sciences Fund, L.P                            
Class Of Stock [Line Items]                            
Issuance of common stock and preferred stock (in shares)       3,756                    
Series B Convertible Preferred Stock | BCIP Life Sciences Associates, L.P                            
Class Of Stock [Line Items]                            
Issuance of common stock and preferred stock (in shares)       384                    
Series B Convertible Preferred Stock | Offering                            
Class Of Stock [Line Items]                            
Number of common stock allowed to purchase       250                    
Combined price of preferred stock and warrant       $ 3,000                    
Maximum                            
Class Of Stock [Line Items]                            
Common stock sales agreement aggregate sales proceeds $ 150,000,000                          
Percentage of common stock held not to exceed for warrant exercises               19.99%            
Maximum | Warrants                            
Class Of Stock [Line Items]                            
Percentage of common stock held not to exceed for warrant exercises               19.99%            
Maximum | Offering                            
Class Of Stock [Line Items]                            
Issuance of common stock and preferred stock (in shares)     16,100,000                      
Warrant issued       5,841,250                    
Maximum | 2017 ATM Agreement                            
Class Of Stock [Line Items]                            
Common stock sales agreement aggregate sales proceeds   $ 150,000,000                        
Commission on gross sales proceeds of common stock   3.00%                        
Minimum                            
Class Of Stock [Line Items]                            
Percentage of common stock to be held for conversion               4.99%            
Minimum | Warrants                            
Class Of Stock [Line Items]                            
Percentage of common stock to be held for exercise of warrants               4.99%