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Equity Plans and Stock-Based Compensation - Stock-Based Compensation Expense (Detail) - USD ($) $ in Thousands	3 Months Ended		9 Months Ended
	Sep. 30, 2020	Sep. 30, 2019	Sep. 30, 2020	Sep. 30, 2019
Deferred Compensation Arrangement With Individual Share Based Payments [Line Items]
Stock-based compensation expense	$ 4,102	$ 4,748	$ 9,968	$ 20,267
Research and Development
Deferred Compensation Arrangement With Individual Share Based Payments [Line Items]
Stock-based compensation expense	778	1,661	(21)	5,817
Selling, General and Administrative
Deferred Compensation Arrangement With Individual Share Based Payments [Line Items]
Stock-based compensation expense	2,504	2,278	7,437	7,828
Restructuring
Deferred Compensation Arrangement With Individual Share Based Payments [Line Items]
Stock-based compensation expense				4,122
Cost of Sales - Product
Deferred Compensation Arrangement With Individual Share Based Payments [Line Items]
Stock-based compensation expense	137	189	452	819
Inventory
Deferred Compensation Arrangement With Individual Share Based Payments [Line Items]
Stock-based compensation expense	$ 683	$ 620	$ 2,100	$ 1,681

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Amount of expense for award under share-based payment arrangement. Excludes amount capitalized.

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