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Intangible Assets, Net - Additional Information (Detail) - USD ($) | 12 Months Ended
--- | ---
Dec. 31, 2020 | Dec. 31, 2019 | Dec. 31, 2018
Finite Lived Intangible Assets [Line Items] |  |  |
Cost of sales - amortization of intangible assets | $ 2,500,000 | $ 9,217,000 | $ 10,862,000
Impairment of intangible assets | 0 | 0 |
Selling, general and administrative | 79,256,000 | 74,986,000 | $ 64,770,000
Asset Purchase Agreement |  |  |
Finite Lived Intangible Assets [Line Items] |  |  |
Upfront payment | 5,000,000 |  |
Upfront payment receivable | 4,000,000 |  |
Additional milestone payments receivable | 250,000,000 |  |
Gain on sale of assets | 6,900,000 |  |
Selling, general and administrative | 2,500,000 |  |
Merck |  |  |
Finite Lived Intangible Assets [Line Items] |  |  |
Cost of sales - amortization of intangible assets | 2,500,000 | $ 9,200,000 |
Symphony Dynamo Holdings Llc | Asset Purchase Agreement |  |  |
Finite Lived Intangible Assets [Line Items] |  |  |
Amount paid to third party | $ 2,500,000 |  |

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- Definition Contingent milestone payment receivable. + References No definition available. + Details
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- Definition Upfront payment. + References No definition available. + Details
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- Definition Upfront payment receivable. + References No definition available. + Details
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- Definition Amount of expense for allocation of cost of intangible asset over its useful life directly used in production of good and rendering of service. + References Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef -Publisher FASB -Name Accounting Standards Codification -Topic 220 -SubTopic 10 -Section S99 -Paragraph 2 -Subparagraph (SX 210.5-03(b)(2)) -URI http://asc.fasb.org/extlink&oid=120395209&loc=SL114868664-224227 + Details
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- Definition Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table. + References No definition available. + Details
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- Definition Amount of gain (loss) from the difference between the sale price or salvage price and the book value of an asset that was sold or retired, and gain (loss) from the write down of assets from their carrying value to fair value. + References Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 28 -Subparagraph (b) -URI http://asc.fasb.org/extlink&oid=121586364&loc=d3e3602-108585 + Details
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- Definition The amount of impairment loss recognized in the period resulting from the write-down of the carrying amount of a finite-lived intangible asset to fair value. + References Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 28 -Subparagraph (b) -URI http://asc.fasb.org/extlink&oid=121586364&loc=d3e3602-108585 Reference 2: http://www.xbrl.org/2009/role/commonPracticeRef -Publisher FASB -Name Accounting Standards Codification -Topic 350 -SubTopic 30 -Section 50 -Paragraph 3 -Subparagraph (b) -URI http://asc.fasb.org/extlink&oid=66006027&loc=d3e16373-109275 + Details
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- Definition The aggregate total costs related to selling a firm's product and services, as well as all other general and administrative expenses. Direct selling expenses (for example, credit, warranty, and advertising) are expenses that can be directly linked to the sale of specific products. Indirect selling expenses are expenses that cannot be directly linked to the sale of specific products, for example telephone expenses, Internet, and postal charges. General and administrative expenses include salaries of non-sales personnel, rent, utilities, communication, etc. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 220 -SubTopic 10 -Section S99 -Paragraph 2 -Subparagraph (SX 210.5-03.4) -URI http://asc.fasb.org/extlink&oid=120395209&loc=SL114868664-224227 + Details
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