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Collaborative Research, Development and License Agreements - Additional Information (Detail) $ in Thousands	1 Months Ended			3 Months Ended	12 Months Ended
	Feb. 29, 2020 USD ($)	Feb. 28, 2019 USD ($)	Feb. 28, 2018 USD ($) Installment	Dec. 31, 2020 USD ($)	Dec. 31, 2020 USD ($)	Dec. 31, 2019 USD ($)	Dec. 31, 2018 USD ($)
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Revenue recognized					$ 46,551	$ 35,219	$ 8,198
Intangible assets, net						2,500
Serum Institute of India Pvt. Ltd. | Collaboration Revenue
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Revenue recognized					900	100	$ 1,400
Reservation Agreement | Coalition for Epidemic Preparedness Innovations
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Revenue recognized				$ 6,300
Reservation fees				6,300
Supply Agreement | Valneva SE
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Deferred revenue				37,100	37,100
Grant Agreement | Bill & Melinda Gates Foundation
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Deferred revenue				1,200	1,200
Grant Agreement | Bill & Melinda Gates Foundation | Maximum
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Proceeds from grant					3,400
Global Access and Strategy/Commitment Agreement | Bill & Melinda Gates Foundation
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Grants receivable				$ 2,200	$ 2,200
Sublicense Agreement | Merck, Sharp & Dohme Corp.
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Aggregate amount payable to acquire intangible assets			$ 21,000
Number of installments | Installment			3
Payment upon obligation	$ 7,000	$ 7,000	$ 7,000
Agreement expiration month and year			2020-04
Intangible assets, net						$ 2,500

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