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Revenue Recognition - Summary of Product Revenue (Detail) - USD ($)
$ in Thousands
 12 Months Ended
Dec. 31, 2020
Dec. 31, 2019
Dec. 31, 2018
Product Revenue Allowance and Revenue Categories [Line Items]      
Total revenues $ 46,551 $ 35,219 $ 8,198
HEPLISAV-B      
Product Revenue Allowance and Revenue Categories [Line Items]      
Total revenues 36,030 34,644 6,812
CpG 1018      
Product Revenue Allowance and Revenue Categories [Line Items]      
Total revenues 3,277    
Product      
Product Revenue Allowance and Revenue Categories [Line Items]      
Total revenues $ 39,307 $ 34,644 $ 6,812