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Outstanding Stock Options and Stock Awards Excluded from Calculation of Net Loss Per Share (Detail) - shares
shares in Thousands
12 Months Ended
Dec. 31, 2020
Dec. 31, 2019
Dec. 31, 2018
Stock Options and Stock Awards      
Outstanding securities not included in diluted net loss per share calculation (in thousands):      
Outstanding securities not included in diluted net loss per share calculation 10,299 9,789 7,344
Warrant Liability      
Outstanding securities not included in diluted net loss per share calculation (in thousands):      
Outstanding securities not included in diluted net loss per share calculation   5,841  
Series B Convertible Preferred Stock      
Outstanding securities not included in diluted net loss per share calculation (in thousands):      
Outstanding securities not included in diluted net loss per share calculation 4,140 4,840