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Equity Plans and Stock-Based Compensation - Additional Information (Detail) - USD ($)
12 Months Ended
May 28, 2020
May 30, 2019
May 31, 2018
May 28, 2014
Dec. 31, 2020
Dec. 31, 2019
Dec. 31, 2018
Jan. 31, 2021
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                
Outstanding stock awards granted         8,505,000 8,006,000    
Total intrinsic value of options exercised         $ 100,000 $ 26,000 $ 200,000  
Total fair value of stock options vested         13,800,000 19,500,000 8,100,000  
Stock-based compensation expense         $ 13,484,000 25,456,000 23,478,000  
Expected dividend yield         0.00%      
Increase in aggregate number of shares of common stock authorized for issuance     600,000          
Restructuring                
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                
Stock-based compensation expense           4,122,000    
Restricted Stock Units (RSUs)                
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                
Stock based compensation expense related to restricted stock         $ 4,900,000      
Aggregate intrinsic value         8,000,000.0      
Total fair value of restricted stock units         $ 4,900,000 $ 7,900,000 19,400,000  
Restricted stock unit awards outstanding         1,794,000 1,784,000    
Employee Stock Option                
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                
Outstanding stock awards granted         117,000      
Performance Based Vesting Condition                
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                
Restricted stock unit awards outstanding         247,000      
Stock-based compensation expense         $ 100,000 $ 500,000 $ 1,900,000  
Maximum | Employee Stock Option                
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                
Expiration period         10 years      
Options vesting period         3 years      
Minimum | Employee Stock Option                
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                
Expiration period         7 years      
Options vesting period         4 years      
2018 Equity Incentive Plan                
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                
Newly reserved shares of common stock     5,000,000          
Shares remaining available for future purchases     140,250          
Outstanding stock awards granted     7,477,619          
Expiration period     7 years          
Shares reserved and approved for issuance         8,349,853      
2018 Equity Incentive Plan | Maximum                
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                
Shares remaining available for future purchases     12,617,869          
Amended 2018 Equity Incentive Plan                
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                
Newly reserved shares of common stock 7,600,000 2,300,000            
Shares remaining available for future purchases   22,517,869            
Dynavax Technologies Corporation 2021 Inducement Award Plan [Member] | Subsequent Event                
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                
Common Stock, Capital Shares Reserved for Future Issuance               1,500,000
Time Based Vesting Schedule                
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                
Total unrecognized compensation cost related to non-vested equity awards         $ 15,900,000      
Total unrecognized compensation cost, weighted-average vesting period         1 year 9 months 18 days      
Performance Based Vesting Schedule                
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                
Total unrecognized compensation cost related to non-vested equity awards         $ 1,200,000      
2014 Employee Stock Purchase Plan                
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                
Total unrecognized compensation cost related to non-vested equity awards         $ 200,000      
Total unrecognized compensation cost, weighted-average vesting period         1 year      
Shares issued to employees         195,334      
Shares remaining available for future purchases         255,583      
2014 Employee Stock Purchase Plan | The commencement of the offer period (generally, the sixteenth day in February or August)                
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                
Purchase price per share as percentage of fair market value of common stock       85.00%        
2014 Employee Stock Purchase Plan | The exercise date, which is the last day of a purchase period (generally, the fifteenth day in February or August)                
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                
Purchase price per share as percentage of fair market value of common stock       85.00%