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Difference between Consolidated Income Tax Benefit and Amount Computed by Federal Statutory Income Tax Rate (Detail) - USD ($)	12 Months Ended
	Dec. 31, 2020	Dec. 31, 2019	Dec. 31, 2018
Income Tax Disclosure [Abstract]
Income tax benefit at federal statutory rate	$ (15,756,000)	$ (32,046,000)	$ (33,366,000)
State tax	(3,194,000)	(3,153,000)	(5,591,000)
Business credits	(773,000)	(1,757,000)	(3,065,000)
Uncertain tax positions	193,000	5,426,000
Deferred compensation charges	809,000	4,600,000	(1,165,000)
Change in valuation allowance	19,009,000	22,715,000	43,134,000
Section 162(m) limitation	473,000	2,439,000
Mark-to-market of warrants	(866,000)	1,575,000
Other	105,000	201,000	53,000
Total income tax expense	$ 0	$ 0	$ 0

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Amount of the difference between reported income tax expense (benefit) and expected income tax expense (benefit) computed by applying the domestic federal statutory income tax rates to pretax income (loss) from continuing operations attributable to tax credits. Including, but not limited to, research credit, foreign tax credit, investment tax credit, and other tax credits.

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Amount of reported income tax expense (benefit) in excess of (less than) expected income tax expense (benefit) computed by applying domestic federal statutory income tax rate to pretax income (loss) from continuing operations, attributable to Tax Cuts and Jobs Act.

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Amount of current income tax expense (benefit) and deferred income tax expense (benefit) pertaining to continuing operations.

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Amount of the difference between reported income tax expense (benefit) and expected income tax expense (benefit) computed by applying the domestic federal statutory income tax rates to pretax income (loss) from continuing operations attributable to increase (decrease) in the valuation allowance for deferred tax assets.

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