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Common Stock, Preferred Stock and Warrants - Additional Information (Detail) - USD ($) |  |  | 1 Months Ended | 3 Months Ended |  |  |
--- | --- | --- | --- | --- | --- | --- | ---
Aug. 06, 2020 | Nov. 03, 2017 | May 31, 2020 | Aug. 31, 2019 | Mar. 31, 2021 | Mar. 31, 2020 | Dec. 31, 2020 | Mar. 11, 2020 | Aug. 12, 2019
Class Of Stock [Line Items] |  |  |  |  |  |  |  |  |
Common stock, shares outstanding |  |  |  |  | 114,563,212 |  | 110,190,000 |  |
Issuance of common stock and preferred stock (in shares) |  |  |  | 18,525,000 |  |  |  |  |
Common stock, par value |  |  |  | $ 0.001 | $ 0.001 |  | $ 0.001 |  |
Preferred stock, par value |  |  |  |  | $ 0.001 |  | $ 0.001 |  |
Net cash proceeds received |  |  |  |  | $ 28,156,000 | $ 14,229,000 |  |  |
Change in fair value of warrant liability |  |  |  |  | $ 25,552,000 | $ (8,610,000) |  |  |
Common Stock |  |  |  |  |  |  |  |  |
Class Of Stock [Line Items] |  |  |  |  |  |  |  |  |
Issuance of common stock and preferred stock (in shares) |  |  |  |  | 2,879,000 | 2,909,000 |  |  |
Number of common stock allowed to purchase |  |  |  |  |  |  |  | 1,000 |
Conversion price per share |  |  |  |  |  |  |  | $ 4.50 |
Warrants |  |  |  |  |  |  |  |  |
Class Of Stock [Line Items] |  |  |  |  |  |  |  |  |
Fair value of derivative liability |  |  |  |  | $ 31,700,000 |  |  |  | $ 7,400,000
Warrants | Other Income, Net |  |  |  |  |  |  |  |  |
Class Of Stock [Line Items] |  |  |  |  |  |  |  |  |
Change in fair value of warrant liability |  |  |  |  | $ 25,600,000 |  |  |  |
Bain Life Sciences |  |  |  |  |  |  |  |  |
Class Of Stock [Line Items] |  |  |  |  |  |  |  |  |
Net cash proceeds received from issuance or sale of equity |  |  |  | $ 35,000,000.0 |  |  |  |  |
Bain Capital Life Sciences Fund, L.P |  |  |  |  |  |  |  |  |
Class Of Stock [Line Items] |  |  |  |  |  |  |  |  |
Issuance of common stock and preferred stock (in shares) |  |  |  | 6,826,266 |  |  |  |  |
Number of common stock allowed to purchase |  |  |  | 2,645,566 |  |  |  |  |
Net cash proceeds received from issuance or sale of equity |  |  |  | $ 31,700,000 |  |  |  |  |
BCIP Life Sciences Associates, L.P |  |  |  |  |  |  |  |  |
Class Of Stock [Line Items] |  |  |  |  |  |  |  |  |
Issuance of common stock and preferred stock (in shares) |  |  |  | 698,734 |  |  |  |  |
Number of common stock allowed to purchase |  |  |  | 270,684 |  |  |  |  |
Net cash proceeds received from issuance or sale of equity |  |  |  | $ 3,200,000 |  |  |  |  |
Offering |  |  |  |  |  |  |  |  |
Class Of Stock [Line Items] |  |  |  |  |  |  |  |  |
Issuance of common stock and preferred stock (in shares) |  |  | 2,100,000 |  |  |  |  |  |
Common stock, par value |  |  | $ 0.001 |  |  |  |  |  |
Number of common stock allowed to purchase |  |  |  | 0.25 |  |  |  |  |
Combined price of common stock and warrant |  |  |  | $ 3.00 |  |  |  |  |
Net cash proceeds received from issuance or sale of equity |  |  | $ 75,400,000 | $ 65,600,000 |  |  |  |  |
Payment of issuance costs |  |  |  | $ 4,500,000 |  |  |  |  |
Price of common stock |  |  | $ 5.00 |  |  |  |  |  |
Offering | Bain Capital Life Sciences Fund, L.P |  |  |  |  |  |  |  |  |
Class Of Stock [Line Items] |  |  |  |  |  |  |  |  |
Issuance of common stock and preferred stock (in shares) |  |  | 1,000,000 |  |  |  |  |  |
2017 ATM Agreement |  |  |  |  |  |  |  |  |
Class Of Stock [Line Items] |  |  |  |  |  |  |  |  |
Issuance of common stock and preferred stock (in shares) |  |  |  |  | 2,878,567 |  |  |  |
Net cash proceeds received |  |  |  |  | $ 28,200,000 |  |  |  |
Remaining proceeds from common stock, under sales agreement |  |  |  |  | $ 120,500,000 |  |  |  |
Series B Convertible Preferred Stock |  |  |  |  |  |  |  |  |
Class Of Stock [Line Items] |  |  |  |  |  |  |  |  |
Issuance of common stock and preferred stock (in shares) |  |  |  | 4,840 |  |  |  |  |
Preferred stock, par value |  |  |  | $ 0.001 |  |  |  |  |
Preferred stock, shares outstanding |  |  |  |  | 4,140 |  | 4,000 |  |
Preferred stock deemed dividend |  |  |  |  | $ 3,300,000 |  |  |  |
Series B Convertible Preferred Stock | Common Stock |  |  |  |  |  |  |  |  |
Class Of Stock [Line Items] |  |  |  |  |  |  |  |  |
Number of common stock allowed to purchase |  |  |  |  | 1,000 |  |  |  |
Series B Convertible Preferred Stock | Bain Capital Life Sciences Fund, L.P |  |  |  |  |  |  |  |  |
Class Of Stock [Line Items] |  |  |  |  |  |  |  |  |
Issuance of common stock and preferred stock (in shares) |  |  |  | 3,756 |  |  |  |  |
Series B Convertible Preferred Stock | BCIP Life Sciences Associates, L.P |  |  |  |  |  |  |  |  |
Class Of Stock [Line Items] |  |  |  |  |  |  |  |  |
Issuance of common stock and preferred stock (in shares) |  |  |  | 384 |  |  |  |  |
Series B Convertible Preferred Stock | Offering |  |  |  |  |  |  |  |  |
Class Of Stock [Line Items] |  |  |  |  |  |  |  |  |
Number of common stock allowed to purchase |  |  |  | 250 |  |  |  |  |
Combined price of preferred stock and warrant |  |  |  | $ 3,000 |  |  |  |  |
Maximum |  |  |  |  |  |  |  |  |
Class Of Stock [Line Items] |  |  |  |  |  |  |  |  |
Common stock sales agreement aggregate sales proceeds | $ 150,000,000 |  |  |  |  |  |  |  |
Maximum | Warrants |  |  |  |  |  |  |  |  |
Class Of Stock [Line Items] |  |  |  |  |  |  |  |  |
Percentage of common stock held not to exceed for warrant exercises |  |  |  |  | 19.99% |  |  |  |
Maximum | Offering |  |  |  |  |  |  |  |  |
Class Of Stock [Line Items] |  |  |  |  |  |  |  |  |
Issuance of common stock and preferred stock (in shares) |  |  | 16,100,000 |  |  |  |  |  |
Warrant issued |  |  |  | 5,841,250 |  |  |  |  |
Maximum | 2017 ATM Agreement |  |  |  |  |  |  |  |  |
Class Of Stock [Line Items] |  |  |  |  |  |  |  |  |
Common stock sales agreement aggregate sales proceeds |  | $ 150,000,000 |  |  |  |  |  |  |
Commission on gross sales proceeds of common stock |  | 3.00% |  |  |  |  |  |  |
Maximum | Series B Convertible Preferred Stock |  |  |  |  |  |  |  |  |
Class Of Stock [Line Items] |  |  |  |  |  |  |  |  |
Percentage of common stock held not to exceed for warrant exercises |  |  |  |  | 19.99% |  |  |  |
Minimum | Warrants |  |  |  |  |  |  |  |  |
Class Of Stock [Line Items] |  |  |  |  |  |  |  |  |
Percentage of common stock to be held for exercise of warrants |  |  |  |  | 4.99% |  |  |  |
Minimum | Series B Convertible Preferred Stock |  |  |  |  |  |  |  |  |
Class Of Stock [Line Items] |  |  |  |  |  |  |  |  |
Percentage of common stock to be held for conversion |  |  |  |  | 4.99% |  |  |  |

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