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Commitments and Contingencies - Additional Information (Detail)
€ in Millions
1 Months Ended 3 Months Ended 9 Months Ended
Sep. 17, 2018
USD ($)
ft²
Feb. 20, 2018
USD ($)
Aug. 31, 2020
USD ($)
Jul. 31, 2019
USD ($)
ft²
Nov. 30, 2009
USD ($)
Mar. 31, 2021
USD ($)
Mar. 31, 2020
USD ($)
Sep. 30, 2020
USD ($)
Mar. 31, 2021
EUR (€)
Dec. 31, 2020
USD ($)
Mar. 29, 2019
USD ($)
Dec. 31, 2004
EUR (€)
Loss Contingencies [Line Items]                        
Tenant improvement allowance             $ (908,000)          
Sublease income           $ 2,022,000 1,926,000          
Cash paid for amounts included in the measurement of operating lease liabilities           1,700,000 1,700,000          
Principal amount including interest paid in kind           $ 180,900,000            
Debt maturity date           Dec. 31, 2023            
Non-cancelable purchase and other commitments           $ 90,900,000            
Letter of credit pledged as security | €                       € 0.2
Collateralized certificate of deposit | €                 € 0.2      
Liability under agreement           390,357,000       $ 294,579,000    
Symphony Dynamo Holdings LLC                        
Loss Contingencies [Line Items]                        
License arrangement contingent consideration percentage         50.00%              
License arrangement upfront payment         $ 50,000,000              
Payment to holdings     $ 2,500,000                  
Symphony Dynamo Holdings LLC | Asset Purchase Agreement                        
Loss Contingencies [Line Items]                        
Liability under agreement           $ 0            
Contingent precommencialization milestone payments percentage           50.00%     50.00%      
CRG Servicing LLC                        
Loss Contingencies [Line Items]                        
Maximum borrowing capacity   $ 175,000,000.0                    
Current borrowing capacity   $ 100,000,000.0                 $ 75,000,000.0  
total contractual obligations           $ 188,100,000            
principal amount           175,000,000.0            
Principal amount including interest paid in kind           5,900,000   $ 180,900,000        
backend facility fee           $ 7,200,000            
Debt maturity date   Dec. 31, 2023           Dec. 31, 2023        
Powell Street Sublease | Emeryville, California (Premises)                        
Loss Contingencies [Line Items]                        
Lease area | ft²       23,976                
Base rent per square feet       $ 3.90                
Lease expiration date       Jun. 30, 2022                
Option to extend           There is no option to extend the sublease term            
Existence of option to extend           false            
Horton Street Master Lease                        
Loss Contingencies [Line Items]                        
Percentage of excess rent paid to landlord           50.00%     50.00%      
Horton Street Master Lease | Emeryville, California (Premises)                        
Loss Contingencies [Line Items]                        
Lease area | ft² 75,662                      
Base rent per square feet $ 4.75                      
Operations commencement date Apr. 01, 2019                      
Tenant improvement allowance $ 8,100,000                      
Initial lease term 12 years                      
Lease option to extend The Horton Street Master Lease has an initial term of 12 years, following the Commencement Date with an option to extend the lease for two successive five-year terms.                      
Renewal term of lease 5 years                      
Horton Street Sublease | Emeryville, California (Premises)                        
Loss Contingencies [Line Items]                        
Lease area | ft²       75,662                
Base rent per square feet       $ 5.50                
Lease expiration date       Mar. 31, 2031                
Option to extend       The Subtenant has no option to extend the sublease term.                
Existence of option to extend       false                
Horton Street Sublease | Emeryville, California (Premises) | Other Income (Expense)                        
Loss Contingencies [Line Items]                        
Sublease income           $ 2,000,000.0 $ 1,900,000