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Revenue Recognition - Summary of Product Revenue (Detail) - USD ($)
$ in Thousands
 3 Months Ended
Mar. 31, 2021
Mar. 31, 2020
Valuation And Qualifying Accounts Disclosure [Line Items]    
Total revenues $ 83,335 $ 10,919
HEPLISAV-B    
Valuation And Qualifying Accounts Disclosure [Line Items]    
Total revenues 8,303 10,514
CpG 1018    
Valuation And Qualifying Accounts Disclosure [Line Items]    
Total revenues 74,582  
Product    
Valuation And Qualifying Accounts Disclosure [Line Items]    
Total revenues $ 82,885 $ 10,514