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Revenue Recognition - Additional Information (Detail)	3 Months Ended
	Mar. 31, 2021	Mar. 31, 2020
HEPLISAV-B
Valuation And Qualifying Accounts Disclosure [Line Items]
Concentration risk, percentage	75.00%	68.00%
HEPLISAV-B | Revenue | Credit Concentration Risk
Valuation And Qualifying Accounts Disclosure [Line Items]
Concentration risk, customer	three largest Customers
CpG 1018
Valuation And Qualifying Accounts Disclosure [Line Items]
Concentration risk, percentage	87.00%
CpG 1018 | Revenue | Credit Concentration Risk
Valuation And Qualifying Accounts Disclosure [Line Items]
Concentration risk, customer	one customer

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Description of risks that arise due to the volume of business transacted with a particular customer. At a minimum, the description informs financial statement users of the general nature of the risk, but excludes "Information about Major Customers" that may be disclosed elsewhere (for instance, segment disclosures).

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For an entity that discloses a concentration risk in relation to quantitative amount, which serves as the "benchmark" (or denominator) in the equation, this concept represents the concentration percentage derived from the division.

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