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Revenue Recognition - Schedule of Revenues from Major Customers (Detail)	3 Months Ended		6 Months Ended
	Jun. 30, 2021	Jun. 30, 2020	Jun. 30, 2021	Jun. 30, 2020
Largest Customer | HEPLISAV-B
Concentration Risk [Line Items]
Percentage of product revenue	28.00%	40.00%	28.00%	25.00%
Second Largest Customer | HEPLISAV-B
Concentration Risk [Line Items]
Percentage of product revenue	21.00%	26.00%	23.00%	24.00%
Third Largest Customer | HEPLISAV-B
Concentration Risk [Line Items]
Percentage of product revenue	16.00%	17.00%	17.00%	17.00%
Largest Collaboration Partner | CpG 1018
Concentration Risk [Line Items]
Percentage of product revenue	63.00%	0.00%	79.00%	0.00%
Second Largest Collaboration Partner | CpG 1018
Concentration Risk [Line Items]
Percentage of product revenue	27.00%	0.00%	15.00%	0.00%

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