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Commitments and Contingencies - Additional Information (Detail)
€ in Millions
1 Months Ended 3 Months Ended 6 Months Ended 9 Months Ended
Sep. 17, 2018
USD ($)
ft²
Sep. 30, 2021
USD ($)
Jul. 31, 2019
USD ($)
ft²
Nov. 30, 2009
USD ($)
Sep. 30, 2021
USD ($)
Sep. 30, 2020
USD ($)
Jun. 30, 2021
Sep. 30, 2021
USD ($)
Sep. 30, 2020
USD ($)
Sep. 30, 2021
EUR (€)
May 31, 2021
USD ($)
Dec. 31, 2020
USD ($)
Dec. 31, 2004
EUR (€)
Loss Contingencies [Line Items]                          
Tenant improvement allowance               $ 0 $ (908,000)        
Sublease income         $ 2,022,000 $ 1,926,000   5,714,000 5,779,000        
Cash paid for amounts included in the measurement of operating lease liabilities               $ 5,200,000 5,100,000        
Long-term debt, net of debt discount                       $ 1,094,000  
Debt maturity date               May 15, 2026          
Letter of credit pledged as security | €                         € 0.2
Collateralized certificate of deposit | €                   € 0.2      
Payment to holdings   $ 500,000                      
Gain on sale of assets         1,000,000 6,851,000   $ 1,000,000 6,851,000        
Selling, general and administrative         26,926,000 21,538,000   $ 70,932,000 61,418,000        
Incremental borrowing rate               10.10%          
Non-cancelable purchase and other commitments   149,300,000     149,300,000     $ 149,300,000          
Asset Purchase Agreement                          
Loss Contingencies [Line Items]                          
Gain on sale of assets         1,000,000     1,000,000          
Upfront payment                       5,000,000  
Upfront payment receivable                       4,000,000  
Additional milestone payments receivable                       $ 250,000,000  
Selling, general and administrative         500,000     500,000          
Symphony Dynamo Holdings LLC                          
Loss Contingencies [Line Items]                          
License arrangement upfront payment       $ 50,000,000                  
TriSalus                          
Loss Contingencies [Line Items]                          
Payment received for Pre-commercialization milestone   1,000,000                      
2.50% Convertible Senior Notes Due 2026                          
Loss Contingencies [Line Items]                          
Aggregate principal amount   225,500,000     225,500,000     225,500,000     $ 225,500,000    
Long-term debt, net of debt discount   $ 5,300,000     $ 5,300,000     $ 5,300,000          
Debt maturity date               May 15, 2026          
Powell Street Sublease | Emeryville, California (Premises)                          
Loss Contingencies [Line Items]                          
Lease area | ft²     23,976                    
Base rent per square feet     $ 3.90                    
Lease expiration date     Jun. 30, 2022                    
Option to extend               There is no option to extend the sublease term          
Existence of option to extend             false            
Horton Street Master Lease                          
Loss Contingencies [Line Items]                          
Percentage of excess rent paid to landlord   50.00%     50.00%     50.00%   50.00%      
Horton Street Master Lease | Emeryville, California (Premises)                          
Loss Contingencies [Line Items]                          
Lease area | ft² 75,662                        
Base rent per square feet $ 4.75                        
Operations commencement date Apr. 01, 2019                        
Tenant improvement allowance $ 8,100,000                        
Initial lease term 12 years                        
Lease option to extend The Horton Street Master Lease has an initial term of 12 years, following the Commencement Date with an option to extend the lease for two successive five-year terms.                        
Renewal term of lease 5 years                        
Horton Street Sublease | Emeryville, California (Premises)                          
Loss Contingencies [Line Items]                          
Lease area | ft²     75,662                    
Base rent per square feet     $ 5.50                    
Lease expiration date     Mar. 31, 2031                    
Option to extend     The Subtenant has no option to extend the sublease term.                    
Existence of option to extend     false                    
Horton Street Sublease | Emeryville, California (Premises) | Other Income (Expense)                          
Loss Contingencies [Line Items]                          
Sublease income         $ 2,000,000.0 $ 1,900,000   $ 5,700,000 $ 5,800,000        
Dusseldorf Lease | Germany                          
Loss Contingencies [Line Items]                          
Operations commencement date   Jan. 01, 2022                      
Initial lease term   10 years     10 years     10 years   10 years      
Lease option to extend   The New Düsseldorf Lease has an initial term of 10 years, beginning on January 1, 2022, with an option to extend the lease for two successive five-year terms.                      
Renewal term of lease   5 years     5 years     5 years   5 years